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prudect name : Atosiban AcetateSynonyms: CAS NO: 90779-69-4Molecular Formula: C43H67N11O12S2Molecular Weight: 994.19Purity: 98% minSolubility: Storage:

June 21, 2017

prudect name : Atosiban Acetate Synonyms: CAS NO: 90779-69-4Molecular Formula: C43H67N11O12S2Molecular Weight: 994.19Purity: 98% minSolubility: Storage: -20°C 1219168-18-9 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18499565

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Ambrisentan is a novel highly selective endothelin receptor antagonist for the treatment of pulmonary arterial hypertension.

prudect name : Ambrisentan is a novel highly selective endothelin receptor antagonist for the treatment of pulmonary arterial hypertension.Ambrisentan Synonyms: CAS NO: 177036-94-1Molecular Formula: C22H22N2O4Molecular Weight: 378.43Purity: ≥99%Solubility: Storage: −20°C…

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AMG 458 also inhibits HGF-mediated c-Met phosphorylation in PC3 and CT26 cells with IC50 of 60 and 120 nM.AMG 458 is observed to bind covalently to liver microsomal proteins from rats and humans in the absence of NADPH. AMG 458 is believed to react with thiol groups in proteins, producing a methoxy quinoline thioether conjugate.A recent study shows that the constitutive phosphorylation of c-Met in H441 is abrogated by AMG 458. The basal and HGF-induced phosphorylation of c-Met in A549 is attenuated by AMG 458. The combination of radiation therapy and AMG 458 treatment is found to synergistically increase apoptosis in the H441 cell line by reduction of p-Akt and p-Erk levels, but not in A549.

prudect name : AMG 458 also inhibits HGF-mediated c-Met phosphorylation in PC3 and CT26 cells with IC50 of 60 and 120 nM.AMG 458 is observed to bind covalently to liver…

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prudect name : AdapaleneSynonyms: CAS NO: 106685-40-9Molecular Formula: C28H28O3Molecular Weight: 412.52Purity: 99%Solubility: Storage: −20°C

prudect name : Adapalene Synonyms: CAS NO: 106685-40-9Molecular Formula: C28H28O3Molecular Weight: 412.52Purity: 99%Solubility: Storage: −20°C 2 years 187227-45-8 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18499400

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[4-[[5-Fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-2-pyrimidinyl]amino]phenyl][(3S)-3-(methylamino)-1-pyrrolidinyl]methanone

prudect name : [4-[[5-Fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-2-pyrimidinyl]amino]phenyl][(3S)-3-(methylamino)-1-pyrrolidinyl]methanoneAZD 5597 Synonyms: CAS NO: 924641-59-8Molecular Formula: C23H28FN7OMolecular Weight: 437.51Purity: 98% minSolubility: In DMSOStorage: -20 oC 501437-28-1 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18499397

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Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.

prudect name : Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of

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prudect name : Azlocillin sodiumSynonyms: CAS NO: 37091-65-9Molecular Formula: C20H22N5NaO6SMolecular Weight: 483.47Purity: ≥99%Solubility: Storage: −20°C

prudect name : Azlocillin sodium Synonyms: CAS NO: 37091-65-9Molecular Formula: C20H22N5NaO6SMolecular Weight: 483.47Purity: ≥99%Solubility: Storage: −20°C 2 years 648903-57-5 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1849926

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prudect name : AzlocillinSynonyms: CAS NO: 37091-66-0Molecular Formula: C20H23N5O6SMolecular Weight: 461.49Purity: ≥99%Solubility: Storage: −20°C

prudect name : Azlocillin Synonyms: CAS NO: 37091-66-0Molecular Formula: C20H23N5O6SMolecular Weight: 461.49Purity: ≥99%Solubility: Storage: −20°C 2 years 377727-87-2 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18499213

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AMG 208 is a selective small-molecule inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. c-Met inhibitor AMG 208 inhibits the ligand-dependent and ligand-independent activation of c-Met, inhibiting its tyrosine kinase activity, which may result in cell growth inhibition in tumors that overexpress c-Met. C-Met encodes the hepatocyte growth factor receptor tyrosine kinase, plays an important role in epithelial cell proliferation and has been shown to be overexpressed in a variety of cancers.

prudect name : AMG 208 is a selective small-molecule inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. c-Met inhibitor AMG 208 inhibits the ligand-dependent and ligand-independent activation of c-Met,…

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AZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. FGFR, up-regulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cellular proliferation, differentiation and survival.

prudect name : AZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor AZD4547 binds to and inhibits FGFR, which may…

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