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Taken together these results strongly support that the expression of the FUS-DDIT3 oncogene is able to block the adipocyte differentiation program of target mesenchymal progenitor cells

May 27, 2017

d with a retroviral vector expressing C/EBPa. To define whether overexpression of C/ EBPa could rescue adipogenesis in FUS-DDIT3 cells, adipocytic differentiation was induced in FUS-DDIT3 MEFs infected either with…

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Taken together these results strongly support that the expression of the FUS-DDIT3 oncogene is able to block the adipocyte differentiation program of target mesenchymal progenitor cells

May 26, 2017

tion reduction, phospholipid catabolism Protein name Glial fibrillary acidic protein isoform 1 Up/down regulation qQQQQ QQQQQ Accession number Cellular localization P14136 Cytoplasm, intermedier filament Molecular function Central nervous system development,…

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CombitTA-FUS-DDIT3 mice were generated by cloning the human FUS-DDIT3 cDNA into the Combi-tTA vector

olymerase was used for PCR. The primers specific to pig APOBEC3F were 59-TGG TCA CAG AGC TGA AGC AG and 59-TTG TTT TGG AAG CAG CCT TT. The semi-nested primer…

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it is tempting to speculate that these NF-kB signaling-dependent targets may play a role in TEL-JAK2-induced leukemogenesis

May 25, 2017

revealed that the local chromatin organization is one of the major players in the in vivo regulation of globin genes expression. There are 5 developmentally specific genes including embryonic, fetal,…

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Fold change values were derived by dividing respective band intensity with GAPDH band intensity and are mentioned below respective bands

e of successful viral subpopulations may require selective pressures not exclusively linked to evolution of V3 variants with altered coreceptor use. high-resolution phylogenetic analysis. ML trees inferred from V1-V2 or…

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HCMV, HSV-1 and HSV-2 have been shown to induce persistence in C. trachomatis co-infections with similar features as those described here for HHV6

May 24, 2017

g adaptor molecules of the TLR/IL1 signaling cascade such as MAP3K7IP7/TAB2. However, 21505263 Microarray procedure miRNA microarray procedure. The oligonucleotide sequences corresponding to 2054 mature miRNAs found in the miRNA…

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Human umbilical vein endothelial cells serve as a natural reservoir for HHV6 allowing active viral particles to survive for prolonged time without productive viral

hich characterizes the pressure equilibration time by fluid transport in the hinge-zone. tp is considerably lower than t, which depicts that WP-1130 site snap-tentacles do not necessarily require elastic instabilities…

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The current generally accepted view is that methylation does not affect phosphatase activity in vitro

May 23, 2017

ansport Electron transport Electron transport chain Electron transport chain Electron transport chain Energy metabolism Lipid metabolism Glutathione conjugation Glycolysis Glycolysis Heme biosynthesis Lipid metabolism Cysteine conjugate-beta lyase; cytoplasmic ER degradation…

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There are increased numbers of mitochondria within cells lacking PINK1 compared to controls

f a mutated allele when it represents 10% or more of the total amplified alleles. Cy5 NHS Ester biological activity ROQUIN coding sequence is not mutated in human AITL We…

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Online supplementary material Generation of PINK1 knockout mice Primary embryonic mouse cultures Results PINK1 is up-regulated following differentiation of human NSCs

May 22, 2017

nes used in this study, two additional tumor cell lines, and on a panel of colon tumor cell lines, comparing it to Ad5. JNJ-26481585 ColoAd1 was over 2 logs more…

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