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prudect name : c-FMS inhibitorSynonyms: 4-Cyano-N-[4-(4-methyl-1-piperazinyl)-2-(4-methyl-1-piperidinyl)phenyl]-1H-pyrrole-2-carboxamideCAS NO: 885704-21-2Molecular Formula: C23H30N6OMolecular Weight: 406.52Purity: 98% minSolubility: In

June 21, 2017

prudect name : c-FMS inhibitor Synonyms: 4-Cyano-N-[4-(4-methyl-1-piperazinyl)-2-(4-methyl-1-piperidinyl)phenyl]-1H-pyrrole-2-carboxamideCAS NO: 885704-21-2Molecular Formula: C23H30N6OMolecular Weight: 406.52Purity: 98% minSolubility: In DMSOStorage: -20°C Ricolinostat References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1850745

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Clarithromycin for the semi-synthetic macrolide antibiotic, with bacterial 50S ribosomal subunits, thus inhibiting its role in protein synthesis and antibiotic production

prudect name : Clarithromycin for the semi-synthetic macrolide antibiotic, with bacterial 50S ribosomal subunits, thus inhibiting its role in protein synthesis and antibiotic productionClarithromycin Synonyms: CAS NO: 81103-11-9Molecular Formula: C38H69NO13Molecular…

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Cobicistat is a drug under experimental investigation for use in the treatment of infection with the human immunodeficiency virus (HIV). Like ritonovir (Norvir), cobicistat is of interest not for its anti-HIV properties, but rather its ability to inhibit liver enzymes that metabolize other medications used to treat HIV, notably elvitegravir, an HIV integrase inhibitor currently under investigation itself. By combining cobicistat with elvitegravir, higher concentrations of elvitgravir are achieved in the body with lower dosing, theoretically enhancing elvitgravir¡¯s viral suppression while diminishing its adverse side-effects. In contrast with ritonavir, the only currently approved booster, cobicistat has no anti-HIV activity of its own¡From Wikipedia.

prudect name : Cobicistat is a drug under experimental investigation for use in the treatment of infection with the human immunodeficiency virus (HIV). Like ritonovir (Norvir), cobicistat is of interest…

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CH5132799 is a novel and selective class I PI3K inhibitor with IC50 of 0.014, 0.12, 0.5, 0.036, 5.3 and 1.6 ¦ÌM for PI3K¦Á, PI3K¦Â, PI3K¦Ä, PI3K¦Ã, PI3K C2¦Â and mTOR, respectively.

prudect name : CH5132799 is a novel and selective class I PI3K inhibitor with IC50 of 0.014, 0.12, 0.5, 0.036, 5.3 and 1.6 ¦ÌM for PI3K¦Á, PI3K¦Â, PI3K¦Ä, PI3K¦Ã, PI3K…

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Department of the Swiss Sandoz clozapine (the predecessor of Novartis) in 1961 and the successful development of antipsychotic drugs and are diphenyl compounds of nitrous Zhuoyan Sheng property

prudect name : Department of the Swiss Sandoz clozapine (the predecessor of Novartis) in 1961 and the successful development of antipsychotic drugs and are diphenyl compounds of nitrous Zhuoyan Sheng…

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CK-636 is an Arp2/3 complex inhibitor with IC50 of 4 ¦ÌM, 24 ¦ÌM and 32 ¦ÌM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively.

prudect name : CK-636 is an Arp2/3 complex inhibitor with IC50 of 4 ¦ÌM, 24 ¦ÌM and 32 ¦ÌM for inhibition of actin polymerization induced by human, fission yeast and…

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2-((4R)-8-chloro-6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide

prudect name : 2-((4R)-8-chloro-6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamideCPI-268456 Synonyms: CAS NO: 1380087-86-4Molecular Formula: C20H15Cl2N3O2 Molecular Weight: 400.264 Purity: 98% minSolubility: DMSOStorage: -20¡æ AG-221 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18507059

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Clemastine fumarate is a highly efficient, low toxicity, long-term, small amount of anti-allergy

prudect name : Clemastine fumarate is a highly efficient, low toxicity, long-term, small amount of anti-allergyClemastine Fumarate Synonyms: CAS NO: 14976-57-9Molecular Formula: C25H30ClNO5Molecular Weight: 459.96Purity: ≥98%Solubility: Storage: −20°C 2 years…

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CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFR¦Â and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2

prudect name : CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFR¦Â and…

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CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models . CB-5083 causes rapid and sustained accumulation of poly-ubiquitin in tumor xenografts after a single administration. CB-5083 showed activity to inhibit tumor growth in multiple rodent models of human cancer. Furthermore, CB-5083 appears to exhibit greater potency over current proteasome inhibitors that further validate targeting p97 and protein homeostasis in the treatment of cancer.

prudect name : CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models ….

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