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Dutasteride is a dual 5-¦Á reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).Dutasteride (100 mg/kg/day) has prostates about half as large as those in intact male rats treated with vehicle alone. Dutasteride is orally bioavailable and because of its mechanism of action it easily overcomes the potential liability of being >99% plasma protein bound.

June 21, 2017

prudect name : Dutasteride is a dual 5-¦Á reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).Dutasteride (100 mg/kg/day) has prostates about half as large as those in intact…

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prudect name : Dorzolomide hydrochlorideSynonyms: CAS NO: 130693-82-2Molecular Formula: C10H16N2O4S3.HClMolecular Weight: 360.89Purity: 98% minSolubility: Storage:

prudect name : Dorzolomide hydrochloride Synonyms: CAS NO: 130693-82-2Molecular Formula: C10H16N2O4S3.HClMolecular Weight: 360.89Purity: 98% minSolubility: Storage: −20°C 2 years PLX4720 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18510311

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Dofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug.Dofetilide blocks HERG currents in excised macro patches of Xenopus oocytes. Dofetilide (1 ¦ÌM) reduces the amplitude of IKr to 61% of control currents in guinea pig cardiomyocytes, as measured by 200-ms test pulses and analysis of the deactivating tail currents of IKr. Dofetilide increases apico-basal disparity of repolarization, due to a more marked increase of ERPs in the apex than in the base in the intact canine heart.

prudect name : Dofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug.Dofetilide blocks HERG currents in excised macro patches of Xenopus oocytes. Dofetilide (1…

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DBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 ¦ÌM.

prudect name : DBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 ¦ÌM.DBeQ; JRF 12 Synonyms: CAS NO: 177355-84-9Molecular Formula: C22H20N4Molecular Weight: 340.42Purity: 98% minSolubility:…

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prudect name : Doripenem hydrateSynonyms: CAS NO: 364622-82-2Molecular Formula: C15H24N4O6S2.H2OMolecular Weight: 438.52Purity: 98% minSolubility: Storage:

prudect name : Doripenem hydrate Synonyms: CAS NO: 364622-82-2Molecular Formula: C15H24N4O6S2.H2OMolecular Weight: 438.52Purity: 98% minSolubility: Storage: −20°C Ro5126766 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18509889

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Danoprevir is a highly potent, orally absorbed inhibitor of the NS3/4A protease for treating chronic HCV infections. This agent is currently in Phase 2b study.

prudect name : Danoprevir is a highly potent, orally absorbed inhibitor of the NS3/4A protease for treating chronic HCV infections. This agent is currently in Phase 2b study.Danoprevir Synonyms: ITMN-191CAS…

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Dorsomorphin is a potent, reversible, selective AMPK inhibitor with Ki of 109 nM in cell-free assays, exhibiting no significant inhibition of several structurally related kinases including ZAPK, SYK, PKC¦È, PKA, and JAK3. Also inhibits type I BMP receptor activity.

prudect name : Dorsomorphin is a potent, reversible, selective AMPK inhibitor with Ki of 109 nM in cell-free assays, exhibiting no significant inhibition of several structurally related kinases including ZAPK,…

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Doxercalciferol (Hectorol; 1.alpha.-Hydroxyvitamin D2) is a synthetic analog of vitamin D; is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA).

prudect name : Doxercalciferol (Hectorol; 1.alpha.-Hydroxyvitamin D2) is a synthetic analog of vitamin D; is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA).Doxercalciferol Synonyms: CAS…

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prudect name : Desmopressin acetateSynonyms: CAS NO: 16789-98-3Molecular Formula: C46H64N14O12S2.2(C2H4O2)Molecular Weight: 1189.32Purity: 98% minSolubility: In

prudect name : Desmopressin acetate Synonyms: CAS NO: 16789-98-3Molecular Formula: C46H64N14O12S2.2(C2H4O2)Molecular Weight: 1189.32Purity: 98% minSolubility: In DMSOStorage: −20°C 3,5-CQA References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18509662

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2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-1H-pyrido[4,3-b]indole

prudect name : 2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-1H-pyrido[4,3-b]indoleDimebolin Synonyms: CAS NO: 3613-73-8Molecular Formula: C21H25N3Molecular Weight: 319.44Purity: 98% minSolubility: Storage: -20°C (+)-Etomoxir sodium salt References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18509642

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