VD/VDR-vd-vdr.com

prudect name : DepofeminSynonyms: CAS NO: 313-06-4Molecular Formula: C26H36O3Molecular Weight: 396.57Purity: 98% minSolubility: Storage: −20°C

June 21, 2017

prudect name : Depofemin Synonyms: CAS NO: 313-06-4Molecular Formula: C26H36O3Molecular Weight: 396.57Purity: 98% minSolubility: Storage: −20°C MDV-3100 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511238

📌

0💬 read more

Danusertib (PHA-739358) is an Aurora kinase inhibitor for Aurora A/B/C with IC50 of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc.

prudect name : Danusertib (PHA-739358) is an Aurora kinase inhibitor for Aurora A/B/C with IC50 of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and…

📌

0💬 read more

Cerubidine (Daunorubicin HCl, Rubidomycin HCl) is the hydrochloride salt of an anthracycline cytotoxic antibiotic produced by a strain of Streptomyces coeruleorubidus (IC50=0.5¦ÌM). On binding to DNA, daunomycin intercalates, with its daunosamine residue directed toward the minor groove. Cerubidine (Daunorubicin HCl, Rubidomycin HCl) has the highest preference for two adjacent G/C base pairs flanked on the 5¡¯ side by an A/T base pair. Cerubidine (Daunorubicin HCl, Rubidomycin HCl) effectively binds to every 3 base pairs and induces a local unwinding angle of 11o, but negligible distortion of helical conformation. Cerubidine (Daunorubicin HCl, Rubidomycin HCl) is chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer. Cerubidine (Daunorubicin HCl, Rubidomycin HCl) is most commonly used to treat specific types of leukaemia (acute myeloid leukemia and acute lymphocytic leukemia). Cerubidine (Daunorubicin HCl, Rubidomycin HCl) was initially isolated from Streptomyces peucetius.

prudect name : Cerubidine (Daunorubicin HCl, Rubidomycin HCl) is the hydrochloride salt of an anthracycline cytotoxic antibiotic produced by a strain of Streptomyces coeruleorubidus (IC50=0.5¦ÌM). On binding to DNA, daunomycin…

📌

0💬 read more

Adriamycin (Doxorubicin) is a topoisomerase II inhibitor with IC50 of 1 and 2 ¦ÌM for the inhibition of MCF-7 and MDA-MB231, respectively. Adriamycin (Doxorubicin) is an anthracycline antibiotic and is used in cancer chemotherapy. Adriamycin (Doxorubicin) inhibits the progression of the enzyme topoisomerase II, which relaxes supercoils in DNA for transcription. Doxorubicin stabilizes the topoisomerase II complex after it has broken the DNA chain for replication, preventing the DNA double helix from being resealed and thereby stopping the process of replication.

prudect name : Adriamycin (Doxorubicin) is a topoisomerase II inhibitor with IC50 of 1 and 2 ¦ÌM for the inhibition of MCF-7 and MDA-MB231, respectively. Adriamycin (Doxorubicin) is an anthracycline…

📌

0💬 read more

Bimatoprost & Latanoprost intermediates

prudect name : Bimatoprost & Latanoprost intermediatesDimethyl (2-oxo-4-phenylbutyl)phosphonate Synonyms: BMPCAS NO: 41162-19-0Molecular Formula: C12H17O4PMolecular Weight: 256.23Purity: 98% minSolubility: Storage: -20¡æ CGP41251 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511168

📌

0💬 read more

Potent non-nucleoside reverse transcriptase inhibitor (NNRTI); an antiretroviral compound designed to prevent or interrupt HIV replication in human cells; safe and tolerable as potential vaginal microbicide.

prudect name : Potent non-nucleoside reverse transcriptase inhibitor (NNRTI); an antiretroviral compound designed to prevent or interrupt HIV replication in human cells; safe and tolerable as potential vaginal microbicide.Dapivirine Synonyms:…

📌

0💬 read more

prudect name : Dimethyl [2-oxo-3-[3-(trifluoromethyl)phenoxy]propyl]phosphonateSynonyms: TVPCAS NO: 54094-19-8Molecular Formula: C12H14F3O5PMolecular Weight: 326.21Purity: 98% minSolubility: Storage:

prudect name : Dimethyl [2-oxo-3-[3-(trifluoromethyl)phenoxy]propyl]phosphonate Synonyms: TVPCAS NO: 54094-19-8Molecular Formula: C12H14F3O5PMolecular Weight: 326.21Purity: 98% minSolubility: Storage: -20¡æ ABR-215062 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511141

📌

0💬 read more

Dovitinib Dilactic acid (TKI258 Dilactic acid) is a highly potent, novel multitargeted growth factor receptor kinase inhibitor with IC50 of 1, 2, 10, 8, 27, 36 nM for FLT3, c-KIT, VEGFR1/2/3, PDGFRß and CSF-1R, respectively. It shows both antitumor and antiangiogenic activities in vivo.It potently inhibits FGFR3 with an inhibitory concentration of 50% (IC50) of 5 nM in in vitro kinase assays and selectively inhibited the growth of B9 cells and human myeloma cell lines expressing wild-type (WT) or activated mutant FGFR3. Antiproliferative activity of Dovitinib Dilactic acid (TKI258 Dilactic acid) against MV4;11 was ~24-fold greater compared with RS4;11, indicating more potent inhibition against cells with constitutively activated FLT3 ITD.

prudect name : Dovitinib Dilactic acid (TKI258 Dilactic acid) is a highly potent, novel multitargeted growth factor receptor kinase inhibitor with IC50 of 1, 2, 10, 8, 27, 36 nM…

📌

0💬 read more

Dasatinib (BMS-354825) is an ATP-competitive, dual SRC/ABL inhibitor. Dasatinib is a potent inhibitor of imatinib-resistant KIT activation loop mutants and induces apoptosis in mast cell and leukemic cell lines expressing these mutations. Dasatinib sensitively inhibits all members of the Src family, including c-Src, Lck, Fyn, and Yes (IC50 < 1.1nmol/L). At higher concentrations (3 to 28 nmol/L), dasatinib also inhibits the Src kinases Abl, c-Kit, PDGFR, and EphA2.

prudect name : Dasatinib (BMS-354825) is an ATP-competitive, dual SRC/ABL inhibitor. Dasatinib is a potent inhibitor of imatinib-resistant KIT activation loop mutants and induces apoptosis in mast cell and leukemic…

📌

0💬 read more

prudect name : DienogestSynonyms: CAS NO: 65928-58-7Molecular Formula: C20H25NO2Molecular Weight: 311.42Purity: 99% minSolubility: Storage: −20°C

prudect name : Dienogest Synonyms: CAS NO: 65928-58-7Molecular Formula: C20H25NO2Molecular Weight: 311.42Purity: 99% minSolubility: Storage: −20°C PP242 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18510965/

📌

0💬 read more