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trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid

June 21, 2017

prudect name : trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acidDGAT-3 Synonyms: CAS NO: 701232-20-4Molecular Formula: C22H26N4O3Molecular Weight: 394.47Purity: 98% minSolubility: In DMSOStorage: -20°C LY-2606368 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511518

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Dronedarone hydrochloride for the treatment of arrhythmia.

prudect name : Dronedarone hydrochloride for the treatment of arrhythmia.Dronedarone hydrochloride Synonyms: CAS NO: 141625-93-6Molecular Formula: C31H44N2O5S.HClMolecular Weight: 593.22Purity: 99%Solubility: Storage: −20°C 2 years EPZ6438 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511498

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prudect name : DacarbazineSynonyms: CAS NO: 4342-03-4Molecular Formula: C6H10N6OMolecular Weight: 182.18Purity: 99%Solubility: Storage: −20°C

prudect name : Dacarbazine Synonyms: CAS NO: 4342-03-4Molecular Formula: C6H10N6OMolecular Weight: 182.18Purity: 99%Solubility: Storage: −20°C 2 years IPI 549 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511463

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Tetrandrine (Fanchinine; Hanfangchin A) is a calcium channel blocker with an IC50 of 38.23¡À 25.77 ¦ÌM. Tetrandrine (Fanchinine; Hanfangchin A) has anti-inflammatory, immunologic and antiallergenic effects. Tetrandrine (Fanchinine; Hanfangchin A) inhibits the degranulation of mast cells. Tetrandrinehas a “Quinidine like” anti-arrhythmic effect. Tetrandrine (Fanchinine; Hanfangchin A) has been isolated from Stephania tetandra and other Chinese and Japanese Herbs. Tetrandrine (Fanchinine; Hanfangchin A) increased populations of both apoptotic sub-G1 and G1 phase. Tetrandrine-induced growth inhibition was associated with induction of Cdk inhibitor p21, inhibition of cyclin D1 and activation of caspase-3. Tetrandrine (Fanchinine; Hanfangchin A) also affected the expression patterns of cytoskeletons including distribution of F-actin and expression level of microtubule.

prudect name : Tetrandrine (Fanchinine; Hanfangchin A) is a calcium channel blocker with an IC50 of 38.23¡À 25.77 ¦ÌM. Tetrandrine (Fanchinine; Hanfangchin A) has anti-inflammatory, immunologic and antiallergenic effects. Tetrandrine…

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prudect name : D-CloprostenolSynonyms: (+)-15(S)-CloprostenolCAS NO: 54276-22-1Molecular Formula: C22H29ClO6Molecular Weight: 424.9Purity: 98% minSolubility: Storage: -20¡æ

prudect name : D-Cloprostenol Synonyms: (+)-15(S)-CloprostenolCAS NO: 54276-22-1Molecular Formula: C22H29ClO6Molecular Weight: 424.9Purity: 98% minSolubility: Storage: -20¡æ ABT199 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511409

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(3S,8S,9S,12S)-3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-2,5,6,10,13-pentaazatetradecanedioic acid 1,14-dimethyl ester

prudect name : (3S,8S,9S,12S)-3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-2,5,6,10,13-pentaazatetradecanedioic acid 1,14-dimethyl esterDes(benzylpyridyl) Atazanavi Synonyms: CAS NO: 1192224-24-0Molecular Formula: C26H43N5O7Molecular Weight: 537.65Purity: 98% minSolubility: in DMSOStorage: -20oC LMI-070 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511348

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JAK3 Inhibitor

prudect name : JAK3 InhibitorDecernotinib (VX-509) Synonyms: CAS NO: 944842-54-0Molecular Formula: Molecular Weight: 392.38Purity: 98% minSolubility: in DMSOStorage: -20oC RG 7388 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511335

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Dabrafenib is an orally bioavailable inhibitor of B-raf (BRAF) protein with potential antineoplastic activity. Dabrafenib selectively binds to and inhibits the activity of B-raf, which may inhibit the proliferation of tumor cells which contain a mutated BRAF gene. B-raf belongs to the the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which may be constitutively activated due to BRAF gene mutations.

prudect name : Dabrafenib is an orally bioavailable inhibitor of B-raf (BRAF) protein with potential antineoplastic activity. Dabrafenib selectively binds to and inhibits the activity of B-raf, which may inhibit…

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Dalbavancin is a novel second-generation lipoglycopeptide antibiotic. It belongs to the same class as vancomycin, the most widely used and one of the few treatments available to patients infected with methicillin-resistant Staphylococcus aureus (MRSA). Dalbavancin is a semisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides currently available, vancomycin and teicoplanin. It possesses in vitro activity against a variety of Gram-positive pathogens including MRSA and methicillin-resistant Staphylococcus epidermidis (MRSE). Dalbavancin was approved in May 2014 for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by certain susceptible bacteria such as Staphylococcus aureus including methicillin-susceptible and methicillin-resistant strains of Streptococcus pyogenes, in intravenous dosage form.

prudect name : Dalbavancin is a novel second-generation lipoglycopeptide antibiotic. It belongs to the same class as vancomycin, the most widely used and one of the few treatments available to…

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Decitabine is an available nucleoside-based DNA methyltransferase (DNMT) inhibitor with IC50 of 490, 400 and 100 nM for A549, LoVo and LoVo-DX cell lines.Decitabine was demonstrated to have a wide range of anti-metabolic activities when tested against cultured cancer cells and to be an effective chemotherapeutic agent for acute myelogenous leukemia. However, because of 5-azacytidine

prudect name : Decitabine is an available nucleoside-based DNA methyltransferase (DNMT) inhibitor with IC50 of 490, 400 and 100 nM for A549, LoVo and LoVo-DX cell lines.Decitabine was demonstrated to…

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