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EPZ015666 shows potent cellular activity that blocks symmetric dimethylation of SmD3 and inhibit proliferation of MCL cell lines (Z-138, Granta-519, Maver-1, Mino, and Jeko-1) with IC50 of 96-904 nM.EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki of 5 nM, >20,000-fold selectivity over other PMTs.

June 21, 2017

prudect name : EPZ015666 shows potent cellular activity that blocks symmetric dimethylation of SmD3 and inhibit proliferation of MCL cell lines (Z-138, Granta-519, Maver-1, Mino, and Jeko-1) with IC50 of…

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prudect name : Ezatiostat; Ter 199; Terrapin 199Synonyms: CAS NO: 168682-53-9Molecular Formula: C27H35N3O6SMolecular Weight: 529.65Purity:

prudect name : Ezatiostat; Ter 199; Terrapin 199 Synonyms: CAS NO: 168682-53-9Molecular Formula: C27H35N3O6SMolecular Weight: 529.65Purity: 98% minSolubility: in DMSOStorage: -20oC TGR1202 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513512

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ENMD-2076 tartrate has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFR¦Á.

prudect name : ENMD-2076 tartrate has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B…

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prudect name : Erlotinib hydrochlorideSynonyms: CAS NO: 183319-69-9Molecular Formula: C22H23N3O4.HClMolecular Weight: 429.90Purity: 99%Solubility: In DMSOStorage:

prudect name : Erlotinib hydrochloride Synonyms: CAS NO: 183319-69-9Molecular Formula: C22H23N3O4.HClMolecular Weight: 429.90Purity: 99%Solubility: In DMSOStorage: −20°C 2 years PF04449913 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513424

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prudect name : ethyl 6-chloronicotinateSynonyms: CAS NO: 49608-01-7Molecular Formula: C8H8ClNO2Molecular Weight: 185.61Purity: 98% minSolubility: Storage:

prudect name : ethyl 6-chloronicotinate Synonyms: CAS NO: 49608-01-7Molecular Formula: C8H8ClNO2Molecular Weight: 185.61Purity: 98% minSolubility: Storage: −20°C PD-0332991 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513392

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For active viral replication, persistent elevations of serum transaminases ALT or liver histology showed chronic active lesions of adult hepatitis B treatment

prudect name : For active viral replication, persistent elevations of serum transaminases ALT or liver histology showed chronic active lesions of adult hepatitis B treatmentEntecavir hydrate Synonyms: CAS NO: 209216-23-9Molecular…

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prudect name : ethyl 6-(pyrrolidin-1-yl)nicotinateSynonyms: CAS NO: 897399-74-5Molecular Formula: C12H16N2O2 Molecular Weight: 220.12 Purity: 98%

prudect name : ethyl 6-(pyrrolidin-1-yl)nicotinate Synonyms: CAS NO: 897399-74-5Molecular Formula: C12H16N2O2 Molecular Weight: 220.12 Purity: 98% minSolubility: Storage: −20°C CX5461 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513268

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4-[(E)-1-[4-(2-Methylaminoethoxy)Phenyl]-2-Phenylbut-1-Enyl]Phenol 4-[(E)-1-[4-(2-Methylaminoethoxy)Phenyl]-2-Phenyl-But-1-Enyl]Phenol;

prudect name : 4-[(E)-1-[4-(2-Methylaminoethoxy)Phenyl]-2-Phenylbut-1-Enyl]Phenol 4-[(E)-1-[4-(2-Methylaminoethoxy)Phenyl]-2-Phenyl-But-1-Enyl]Phenol;Endoxifen Synonyms: CAS NO: 110025-28-0Molecular Formula: C25H27NO2Molecular Weight: 373.49Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years LDN-193189 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513244

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Eflornithine HCl acid can irreversibly inhibit ODC activity in the skin, the enzyme essential for the polyamine synthesis enzyme.

prudect name : Eflornithine HCl acid can irreversibly inhibit ODC activity in the skin, the enzyme essential for the polyamine synthesis enzyme.Eflornithine HCl Synonyms: CAS NO: 96020-91-6Molecular Formula: C6H12F2N2O2.HCl.H2OMolecular Weight:…

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intermediates of Anidulafungin

prudect name : intermediates of AnidulafunginEchinocandin B Synonyms: CAS NO: 79411-15-7Molecular Formula: C34H51N7O15Molecular Weight: 797.81Purity: 70% minSolubility: In DMSOStorage: -20¡æ GDC 0853 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513211

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