Epoxomicin is a potent anti-tumor agent isolated from Actinomycetes that is used as a selective and irreversible inhibitor of the 20S proteasome. It inhibits proteasome activity in cell growth assays with an IC50 value of 4 nM and demonstrates potent cytotoxicity against B16-F10, HCT116, and Moser solid tumor cells, as well as P388 and K562 leukemia cells with IC50 values ranging from 2-44 nM.

June 21, 2017

prudect name : Epoxomicin is a potent anti-tumor agent isolated from Actinomycetes that is used as a selective and irreversible inhibitor of the 20S proteasome. It inhibits proteasome activity in…

๐Ÿ“Œ
0๐Ÿ’ฌ read more

Entospletinib, also known as GS-9973, is a highly selective and orally efficacious Syk inhibitor which is currently undergoing clinical evaluation for autoimmune and oncology indications.

prudect name : Entospletinib, also known as GS-9973, is a highly selective and orally efficacious Syk inhibitor which is currently undergoing clinical evaluation for autoimmune and oncology indications.Entospletinib Synonyms: GS-9973;…

๐Ÿ“Œ
0๐Ÿ’ฌ read more

Eptifibatide is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.

prudect name : Eptifibatide is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.Eptifibatide Synonyms: CAS NO: 188627-80-7 148031-34-9Molecular Formula: C35H49N11O9S2Molecular Weight: 831.96Purity: 98% minSolubility: in DMSOStorage: -20oC AZD 7762…

๐Ÿ“Œ
0๐Ÿ’ฌ read more

prudect name : ECBC hcl; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1)Synonyms: CAS NO: 1029890-89-8Molecular Formula: C34H51N7O15.HClMolecular Weight:

prudect name : ECBC hcl; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1) Synonyms: CAS NO: 1029890-89-8Molecular Formula: C34H51N7O15.HClMolecular Weight: 834.27Purity: 90% minSolubility: Storage: -20oC BAY-41-2272 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/18513795

๐Ÿ“Œ
0๐Ÿ’ฌ read more

EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity with Ki value of 2.5ยกร€0.5 nM. IC50 Value: 2.5ยกร€0.5 nM (PRC2-containing wild-type EZH2)

prudect name : EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity with Ki value of 2.5ยกร€0.5 nM. IC50 Value: 2.5ยกร€0.5 nM (PRC2-containing wild-type EZH2)EPZ6438;…

๐Ÿ“Œ
0๐Ÿ’ฌ read more

ENOblock(AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo.

prudect name : ENOblock(AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis…

๐Ÿ“Œ
0๐Ÿ’ฌ read more

N-(Diaminomethylidene)-2-Methyl-5-Methylsulfonyl-4-Pyrrol-1-Ylbenzamide N-(Diaminomethylene)-2-Methyl-5-Methylsulfonyl-4-Pyrrol-1-Yl-Benzamide; N-(Diaminomethylene)-2-Methyl-5-Methylsulfonyl-4-(1-Pyrrolyl)Benzamide; N-(Diaminomethylene)-5-Mesyl-2-Methyl-4-Pyrrol-1-Yl-Benzamide

prudect name : N-(Diaminomethylidene)-2-Methyl-5-Methylsulfonyl-4-Pyrrol-1-Ylbenzamide N-(Diaminomethylene)-2-Methyl-5-Methylsulfonyl-4-Pyrrol-1-Yl-Benzamide; N-(Diaminomethylene)-2-Methyl-5-Methylsulfonyl-4-(1-Pyrrolyl)Benzamide; N-(Diaminomethylene)-5-Mesyl-2-Methyl-4-Pyrrol-1-Yl-BenzamideENIPORIDE Synonyms: CAS NO: 176644-21-6Molecular Formula: C14H16N4O3SMolecular Weight: 320.37Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years CB 5083 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/18513700

๐Ÿ“Œ
0๐Ÿ’ฌ read more

Etofenamate is a non-steroidal anti-inflammatory drug used for the treatment joint and muscular pain.

prudect name : Etofenamate is a non-steroidal anti-inflammatory drug used for the treatment joint and muscular pain.Etofenamate Synonyms: CAS NO: 30544-47-9Molecular Formula: C18H18F3NO4Molecular Weight: 369.33Purity: 98% minSolubility: in DMSOStorage: -20oC…

๐Ÿ“Œ
0๐Ÿ’ฌ read more

prudect name : Eravacycline TP-434Synonyms: CAS NO: 1207283-85-9Molecular Formula: C27H31FN4O8Molecular Weight: 558.56Purity: 98% minSolubility: In

prudect name : Eravacycline TP-434 Synonyms: CAS NO: 1207283-85-9Molecular Formula: C27H31FN4O8Molecular Weight: 558.56Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years JNJ 40411813 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/18513680

๐Ÿ“Œ
0๐Ÿ’ฌ read more

prudect name : Ertapenem SodiumSynonyms: CAS NO: 153773-82-1Molecular Formula: C22H25N3O7S.NaMolecular Weight: 498.51Purity: 98% minSolubility: Storage:

prudect name : Ertapenem Sodium Synonyms: CAS NO: 153773-82-1Molecular Formula: C22H25N3O7S.NaMolecular Weight: 498.51Purity: 98% minSolubility: Storage: −20°C LCL 161 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/18513669

๐Ÿ“Œ
0๐Ÿ’ฌ read more