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prudect name : EstroneSynonyms: CAS NO: 53-16-7Molecular Formula: C18H22O2Molecular Weight: 270.37Purity: 98% minSolubility: Storage: −20°C

June 21, 2017

prudect name : Estrone Synonyms: CAS NO: 53-16-7Molecular Formula: C18H22O2Molecular Weight: 270.37Purity: 98% minSolubility: Storage: −20°C GSK690693 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18514182

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prudect name : EstriolSynonyms: CAS NO: 50-27-1Molecular Formula: C18H24O3Molecular Weight: 288.38Purity: 98% minSolubility: Storage: −20°C

prudect name : Estriol Synonyms: CAS NO: 50-27-1Molecular Formula: C18H24O3Molecular Weight: 288.38Purity: 98% minSolubility: Storage: −20°C AMG-706 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18514146

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prudect name : Ethynyl estradiolSynonyms: CAS NO: 57-63-6Molecular Formula: C20H24O2Molecular Weight: 296.41Purity: 98% minSolubility: Storage:

prudect name : Ethynyl estradiol Synonyms: CAS NO: 57-63-6Molecular Formula: C20H24O2Molecular Weight: 296.41Purity: 98% minSolubility: Storage: −20°C ITI-007 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18514123

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prudect name : EthyliminumSynonyms: CAS NO: 1506-47-4Molecular Formula: C10H14N4O4Molecular Weight: 254.24Purity: 99%Solubility: Storage: −20°C

prudect name : Ethyliminum Synonyms: CAS NO: 1506-47-4Molecular Formula: C10H14N4O4Molecular Weight: 254.24Purity: 99%Solubility: Storage: −20°C 2 years NSC-405020 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18514063

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5,11-Dimethyl-6H-pyrido[4,3-b]carbazole

prudect name : 5,11-Dimethyl-6H-pyrido[4,3-b]carbazoleEllipticine Synonyms: CAS NO: 519-23-3Molecular Formula: C17H14N2Molecular Weight: 246.31Purity: 98% minSolubility: In DMSOStorage: -20 oC ONT-380 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18514005

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EPZ-5676 is a small molecule inhibitor of histone methyltransferase with potential antineoplastic activity. Upon intravenous administration, EPZ-5676 specifically blocks the activity of the histone lysine-methyltransferase DOT1L, thereby inhibiting the methylation of nucleosomal histone H3 on lysine 79 (H3K79) that is bound to the mixed lineage leukemia (MLL) fusion protein which targets genes and blocks the expression of leukemogenic genes. This eventually leads to an induction of apoptosis in the leukemic cells bearing the MLL gene translocations. DOT1L, a non-SET domain-containing histone methyltransferase, specifically methylates H3K79 and plays a key role in normal cell differentiation and in the development of leukemia with MLL gene rearrangement on chromosome 11 and promotes the expression of leukemia-causing genes.

prudect name : EPZ-5676 is a small molecule inhibitor of histone methyltransferase with potential antineoplastic activity. Upon intravenous administration, EPZ-5676 specifically blocks the activity of the histone lysine-methyltransferase DOT1L, thereby…

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prudect name : Estradiol benzoateSynonyms: CAS NO: 50-50-0Molecular Formula: C25H28O3Molecular Weight: 376.49Purity: 98% minSolubility: Storage:

prudect name : Estradiol benzoate Synonyms: CAS NO: 50-50-0Molecular Formula: C25H28O3Molecular Weight: 376.49Purity: 98% minSolubility: Storage: −20°C SCH 420814 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513969

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Everolimus(RAD001), is a 40-O-(2-hydroxyethyl) derivative of rapamycin with immunosuppressant and anti-angiogenic properties, which exhibits improved aqueous solubility relative to the parent compound for oral administration. In cells, Everolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of mTOR. Inhibition of mTOR activation results in the inhibition of T lymphocyte activation and proliferation associated with antigen and cytokine (IL-2, IL-4, and IL-15) stimulation and the inhibition of antibody production

prudect name : Everolimus(RAD001), is a 40-O-(2-hydroxyethyl) derivative of rapamycin with immunosuppressant and anti-angiogenic properties, which exhibits improved aqueous solubility relative to the parent compound for oral administration. In cells,…

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Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production. Eltrombopag was approved by FDA in November 20, 2008.

prudect name : Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110),…

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(3aS,4R,9bR)-1,2,3,3a,4,9b-Hexahydro-4-(4-hydroxyphenyl)cyclopenta[c][1]benzopyran-8-ol

prudect name : (3aS,4R,9bR)-1,2,3,3a,4,9b-Hexahydro-4-(4-hydroxyphenyl)cyclopenta[c][1]benzopyran-8-olErteberel Synonyms: CAS NO: 533884-09-2Molecular Formula: C18H18O3Molecular Weight: 282.33Purity: 98% minSolubility: In DMSOStorage: -20°C R207910 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513887

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