GLPG0634 (analog) is a pan JAK inhibitor with IC50s of 50-200 nM for JAK1/JAK2/JAK3; more information can be found in the reference patents.

June 21, 2017

prudect name : GLPG0634 (analog) is a pan JAK inhibitor with IC50s of 50-200 nM for JAK1/JAK2/JAK3; more information can be found in the reference patents.GLPG0634 (Filgotinib) Synonyms: CAS NO:…

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GBR 12935 2Hcl is a potent, and selective dopamine reuptake inhibitor.

prudect name : GBR 12935 2Hcl is a potent, and selective dopamine reuptake inhibitor.GBR 12935 dihydrochloride Synonyms: CAS NO: 67469-81-2Molecular Formula: C28H34N2O.2(HCl)Molecular Weight: 487.51Purity: 98% minSolubility: in DMSOStorage: -20oC SCH58261…

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GSK1070916 selectively inhibits Aurora B and Aurora C with Ki of 0.38 nM and 1.5 nM over Aurora A with Ki of 490 nM. Inhibition of Aurora B and Aurora C is time-dependent, with an enzyme-inhibitor dissociation half-life of >480 min and 270 min respectively. In addition, GSK1070916 is also a competitive inhibitor with respect to ATP.

prudect name : GSK1070916 selectively inhibits Aurora B and Aurora C with Ki of 0.38 nM and 1.5 nM over Aurora A with Ki of 490 nM. Inhibition of Aurora…

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Synonyms :GW 7647X; GWalpha 7647; 2-[[4-[2-[[(Cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methylpropanoic acid

prudect name : Synonyms :GW 7647X; GWalpha 7647; 2-[[4-[2-[[(Cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methylpropanoic acidGW 7647 Synonyms: CAS NO: 265129-71-3Molecular Formula: C29H46N2O3SMolecular Weight: 502.75Purity: 98% minSolubility: In DMSOStorage: −20°C GSK-2830371 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/18516090

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GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases.

prudect name : GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively,…

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Chemical Name: 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one

prudect name : Chemical Name: 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-oneGW 441756 Synonyms: CAS NO: 504433-23-2Molecular Formula: C17H13N3OMolecular Weight: 275.31Purity: 98% minSolubility: In DMSOStorage: −20°C PF 06463922 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/1851606

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Synonyms: N-[(4,6-Dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-methyl-1-((1S)-1-methylpropyl)-6-[6-(1-;GSK126 – inhibitor of histone methyltransferase EZH2;

prudect name : Synonyms: N-[(4,6-Dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-methyl-1-((1S)-1-methylpropyl)-6-[6-(1-;GSK126 – inhibitor of histone methyltransferase EZH2;gsk 126 gsk126 Synonyms: CAS NO: 1346574-57-9Molecular Formula: C31H38N6O2Molecular Weight: 526.67Purity: 98% minSolubility: In DMSOStorage: -20°C AN2728 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/18516052

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3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one

prudect name : 3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-oneGW 5074 Synonyms: CAS NO: 220904-83-6Molecular Formula: C15H8Br2INO2Molecular Weight: 520.94Purity: 98% minSolubility: In DMSOStorage: −20°C AZD5438 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/18516050

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prudect name : Gonadorelin acetateSynonyms: CAS NO: 34973-08-5Molecular Formula: C55H75N17O13.C2H4O2Molecular Weight: 1242.34Purity: 98% minSolubility: Storage:

prudect name : Gonadorelin acetate Synonyms: CAS NO: 34973-08-5Molecular Formula: C55H75N17O13.C2H4O2Molecular Weight: 1242.34Purity: 98% minSolubility: Storage: -20°C DX 8951 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/18516046

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Gambogic Acid is a caged xanthone that is derived from Garcinia hanburyi and functions as a strong apoptotic inducer in many types of cancer cells by inhibiting human Bcl-2 family proteins and activating caspases. Gambogic Acid also blocks Kir2.1 channels with EC50 of ยกรœ 100 nM.Gambogic Acid significantly inhibits human umbilical vein endothelial cell (HUVEC) proliferation, migration, invasion, tube formation, and micro-vessel growth at nM concentration.

prudect name : Gambogic Acid is a caged xanthone that is derived from Garcinia hanburyi and functions as a strong apoptotic inducer in many types of cancer cells by inhibiting…

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