VD/VDR-vd-vdr.com

Chemical Name: 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine hydrochloride

June 21, 2017

prudect name : Chemical Name: 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine hydrochlorideHA 1100 hydrochloride Synonyms: CAS NO: 105628-72-6Molecular Formula: C14H17N3O3S.HClMolecular Weight: 343.83Purity: 98% minSolubility: In DMSOStorage: −20°C MK 0974 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18519069

📌

0💬 read more

prudect name : HQL 79Synonyms: 4-(Diphenylmethoxy)-1-[3-(2H-tetrazol-5-yl)propyl]piperidineCAS NO: 162641-16-9Molecular Formula: C22H27N5OMolecular Weight: 377.48Purity: 98% minSolubility: In

prudect name : HQL 79 Synonyms: 4-(Diphenylmethoxy)-1-[3-(2H-tetrazol-5-yl)propyl]piperidineCAS NO: 162641-16-9Molecular Formula: C22H27N5OMolecular Weight: 377.48Purity: 98% minSolubility: In DMSOStorage: −20°C FG 4592 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18519043

📌

0💬 read more

Biological Activity Inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM). Displays uncompetitive inhibition. Also inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 ¦ÌM). Stabilizes p53 and inhibits cancer cell growth; induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines.

prudect name : Biological Activity Inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM). Displays uncompetitive inhibition. Also inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 ¦ÌM). Stabilizes p53…

📌

0💬 read more

Protein kinase A (PKA) regulates multiple signal transduction events via protein phosphorylation and is integral to all cellular responses involving the cyclic AMP second messenger system. H-89 is a potent, cell permeable inhibitor of PKA that demonstrates an IC50 value of 0.14 µM and a Ki value of 48 nM in standard kinase assays.While widely used to disrupt PKA signaling, the inhibitory activity of H-89 is non-selective. H-89 also inhibits S6K1, MSK1, ROCK-II, PKB¦Á, and MAPKAP-K1b with IC50 values of 0.08, 0.12, 0.27, 2.6, and 2.8 µM, respectively.

prudect name : Protein kinase A (PKA) regulates multiple signal transduction events via protein phosphorylation and is integral to all cellular responses involving the cyclic AMP second messenger system. H-89…

📌

0💬 read more

HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2(IC50=23.3 nM) and the G2019S mutant(IC50=3.2 nM)

prudect name : HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2(IC50=23.3 nM) and the G2019S mutant(IC50=3.2 nM)HG-10-102-01 Synonyms: CAS NO: 1351758-81-0Molecular Formula: C17H20ClN5O3Molecular Weight: 377.83Purity: 98% minSolubility: In…

📌

0💬 read more

Hydroxyurea tablets can be reduced to prevent deoxynucleotidyl nucleotide, purine and pyrimidine bases interfere with the biosynthesis, DNA synthesis selectively impede.

prudect name : Hydroxyurea tablets can be reduced to prevent deoxynucleotidyl nucleotide, purine and pyrimidine bases interfere with the biosynthesis, DNA synthesis selectively impede.Hydroxyurea Synonyms: CAS NO: 127-07-1Molecular Formula: CH4N2O2Molecular…

📌

0💬 read more

prudect name : HydroxycamptothecinSynonyms: CAS NO: 19685-09-7Molecular Formula: C20H16N2O5Molecular Weight: 364.357Purity: ≥99%Solubility: Storage: −20°C

prudect name : Hydroxycamptothecin Synonyms: CAS NO: 19685-09-7Molecular Formula: C20H16N2O5Molecular Weight: 364.357Purity: ≥99%Solubility: Storage: −20°C 2 years MLN 4924 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18518933

📌

0💬 read more

prudect name : HexarelinSynonyms: CAS NO: 140703-51-1Molecular Formula: C47H58N12O6Molecular Weight: 887.04Purity: 98% minSolubility: Storage: -20°C

prudect name : Hexarelin Synonyms: CAS NO: 140703-51-1Molecular Formula: C47H58N12O6Molecular Weight: 887.04Purity: 98% minSolubility: Storage: -20°C VX 765 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18518906

📌

0💬 read more

HPGDS inhibitor 1 is a novel and selective Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50 Value of 0.7 nM.

prudect name : HPGDS inhibitor 1 is a novel and selective Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50 Value of 0.7 nM.HPGDS inhibitor-1 Synonyms: CAS NO: 1033836-12-2Molecular Formula:…

📌

0💬 read more

Biological Activity:Cell-permeable inhibitor of Bcl-2 protein (IC50 ~ 9 ¦ÌM); acts by binding to the surface pocket. Disrupts Bax/Bcl-2 interaction and induces apoptosis of tumor cells. Also binds to the antiapoptotic Blc-2 proteins Bcl-XL and Bcl-w.

prudect name : Biological Activity:Cell-permeable inhibitor of Bcl-2 protein (IC50 ~ 9 ¦ÌM); acts by binding to the surface pocket. Disrupts Bax/Bcl-2 interaction and induces apoptosis of tumor cells. Also…

📌

0💬 read more