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Thiomyristoyl is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM.

June 21, 2017

prudect name : Thiomyristoyl is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM.Thiomyristoyl Synonyms: CAS NO: 1429749-41-6Molecular Formula: C34H51N3O3SMolecular Weight: 581.85Purity: 98% minSolubility: DMSOStorage: -20°C web…

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prudect name : TP-808Synonyms: CAS NO: 852821-06-8Molecular Formula: C26H34N2O5SiMolecular Weight: 482.64Purity: 98% minSolubility: in DMSOStorage:

prudect name : TP-808 Synonyms: CAS NO: 852821-06-8Molecular Formula: C26H34N2O5SiMolecular Weight: 482.64Purity: 98% minSolubility: in DMSOStorage: -20oC web site: www.medchemexpress.com

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liquid crystal intermediates

prudect name : liquid crystal intermediatestrans-4-[2-(4-Pentylcyclohexyl)ethyl]cyclohexanone Synonyms: CAS NO: 121040-08-2Molecular Formula: C19H34OMolecular Weight: 278.47Purity: 99% minSolubility: Storage: web site: www.medchemexpress.com

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TG-101348 is a potent, highly selective and ATP- competitive JAK2 inhibitor with an IC50 of 3 nM for JAK2 and JAK2 V617F. Besides, TG-101348 inhibits Flt3 and Ret with IC50 values of 15 and 48 nM, respectively.

prudect name : TG-101348 is a potent, highly selective and ATP- competitive JAK2 inhibitor with an IC50 of 3 nM for JAK2 and JAK2 V617F. Besides, TG-101348 inhibits Flt3 and…

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TIC10(ONC-201) is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier.

prudect name : TIC10(ONC-201) is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier.TIC10(ONC-201) Synonyms: CAS NO: 1616632-77-9Molecular…

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prudect name : TeniposideSynonyms: CAS NO: 29767-20-2Molecular Formula: C32H32O13SMolecular Weight: 656.66Purity: 98% minSolubility: In DMSOStorage:

prudect name : Teniposide Synonyms: CAS NO: 29767-20-2Molecular Formula: C32H32O13SMolecular Weight: 656.66Purity: 98% minSolubility: In DMSOStorage: −20°C web site: www.medchemexpress.com

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liquid crystal intermediates

prudect name : liquid crystal intermediatestrans-(4-Propylcyclohexyl)benzene Synonyms: CAS NO: 61203-94-9Molecular Formula: C15H22Molecular Weight: 202.34Purity: 99% minSolubility: Storage: web site: www.medchemexpress.com

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Trelagliptin is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). Two Phase II clinical studies have been completed with Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus. Phase III clinical studies with trelagliptin in Japan to evaluate its safety and efficacy in a once-weekly oral treatment regimen. Currently, all available DPP-4 inhibitors are dosed once-daily. A once-weekly treatment, such as trelagliptin, would provide patients with a convenient treatment alternative and has the potential to improve treatment compliance.

prudect name : Trelagliptin is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). Two Phase II clinical studies have…

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TGR-1202, also known as RP5264 , is a highly specific, orally available, PI3K delta inhibitor, targeting the delta isoform with nanomolar potency and several fold selectivity over the alpha, beta, and gamma isoforms of PI3K. Inhibition of PI3K delta signaling with TGR-1202 has demonstrated robust activity in numerous pre-clinical models and primary cells from patients with hematologic malignancies.

prudect name : TGR-1202, also known as RP5264 , is a highly specific, orally available, PI3K delta inhibitor, targeting the delta isoform with nanomolar potency and several fold selectivity over…

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N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-alaninamide

prudect name : N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-alaninamideTAPI-1 Synonyms: CAS NO: 171235-71-5Molecular Formula: C26H37N5O5Molecular Weight: 499.60Purity: 98% minSolubility: In DMSOStorage: -20 oC web site: www.medchemexpress.com

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