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(5E)-Latanoprost;trans Latanoprost;5,6-trans-Latanoprost;(5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester

June 21, 2017

prudect name : (5E)-Latanoprost;trans Latanoprost;5,6-trans-Latanoprost;(5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Estertrans-Latanoprost Synonyms: 5,6-trans-LatanoprostCAS NO: 913258-34-1Molecular Formula: C26H40O5Molecular Weight: 432.59Purity: 98% minSolubility: Storage: -20°C web site: www.medchemexpress.com

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Synonyms: (5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; Isoproyl (E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoate; (5E,15S)-Latanoprost; 5,6-trans-(15S)-Latanoprost;

prudect name : Synonyms: (5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; Isoproyl (E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoate; (5E,15S)-Latanoprost; 5,6-trans-(15S)-Latanoprost;trans-(15S)-Latanoprost Synonyms: CAS NO: 1235141-39-5Molecular Formula: C26H40O5Molecular Weight: 432.59Purity: 98% minSolubility: Storage: -20°C web site: www.medchemexpress.com

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TMP269 is a novel and selective class IIa histone deacetylase inhibitor with IC50s of 126/80/36/9 nM for HDAC 4/5/7/9, respectively; 20-400 fold selectivity over class1 HDACs

prudect name : TMP269 is a novel and selective class IIa histone deacetylase inhibitor with IC50s of 126/80/36/9 nM for HDAC 4/5/7/9, respectively; 20-400 fold selectivity over class1 HDACsTMP269 Synonyms:…

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prudect name : Triptorelin acetateSynonyms: CAS NO: 140194-24-7Molecular Formula: C64H82N18O13.C2H4O2Molecular Weight: 1371.52Purity: 98% minSolubility: Storage:

prudect name : Triptorelin acetate Synonyms: CAS NO: 140194-24-7Molecular Formula: C64H82N18O13.C2H4O2Molecular Weight: 1371.52Purity: 98% minSolubility: Storage: -20°C web site: www.medchemexpress.com

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TGX-221 is a potent, selective, and cell permeable inhibitor of PI3K p110¦Â .

prudect name : TGX-221 is a potent, selective, and cell permeable inhibitor of PI3K p110¦Â .TGX 221 Synonyms: CAS NO: 663619-89-4Molecular Formula: C21H24N4O2Molecular Weight: 363.40Purity: 98% minSolubility: In DMSOStorage: -20°C…

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TG101209 is a potent and small molecule JAK2-selective kinase inhibitor with IC50 of 6, 25, 17 and 169 nM for JAK2, FLT3, RET and JAK3, respectively.TG101209 potently prevents myeloproliferative disorder-related JAK2V617F and MPLW515L/K mutations. Besides, TG101209 suppressed the activation of STAT3 and survivin expression and sensitized HCC2429 and H460 cells to radiation in clonogenic assays. After treatment with TG101209, phospho-ERK protein levels were decreased in both HCC2429 and H460 cells. HCC2429 cells transfected with KRAS-12V mutant were more resistant to radiation- and TG101209-evoked apoptosis than wild-type control cells. In vivo, addition of TG101209 to radiation in lung xenografts produced a striking tumor growth delay (>10 days) compared with radiation alone and was well tolerated. Immunohistochemistry staining of tumor sections showed that TG101209 enhanced apoptosis and decreased cell proliferation and vascular density, suggesting that TG101209 also has antiangiogenic effects.

prudect name : TG101209 is a potent and small molecule JAK2-selective kinase inhibitor with IC50 of 6, 25, 17 and 169 nM for JAK2, FLT3, RET and JAK3, respectively.TG101209 potently…

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prudect name : Tyrosine kinase inhibitorSynonyms: CAS NO: 1021950-26-4Molecular Formula: C31H31FN6O5Molecular Weight: 586.61Purity: 98% minSolubility:

prudect name : Tyrosine kinase inhibitor Synonyms: CAS NO: 1021950-26-4Molecular Formula: C31H31FN6O5Molecular Weight: 586.61Purity: 98% minSolubility: In DMSOStorage: -20°C web site: www.medchemexpress.com

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TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor (IC50= 0.1¦ÌM, Ki= 40nM). In addition, TTP 22 shows selectivity for CK2 over JNK3, ROCK1, and MET (inhibitory effects displayed at greater than 10 ¦ÌM). TTP 22 is highly conserved serine/threonine protein kinase that is also involved in cell proliferation, cell differentiation and apoptosis.

prudect name : TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor (IC50= 0.1¦ÌM, Ki= 40nM). In addition, TTP 22 shows selectivity for CK2 over JNK3, ROCK1,…

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Tafluprost ethyl amide is derived from 17-phenyl trinor Prostaglandin F2¦Á(17-phenyl trinor PGF2¦Á). A number of 17-phenyl trinor PGF2¦Á derivatives have been approved for the treatment of glaucoma.1,2,3,4 Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.5 Alternatively, it was recently reported that analogs incorporating a 15-deoxy-15,15-difluoro modification also had a favorable ophthalmic activity profile.6 Tafluprost is a 2-series, 16-phenoxy analog of PGF2¦Á with the 15,15-difluoro substitution. As a free acid, Tafluprost is a very potent FP receptor agonist (Ki = 0.4 nM).6 Ethyl amides of PGs tend to increase lipid solubility, to improve uptake into tissues and to further lower the effective concentration

prudect name : Tafluprost ethyl amide is derived from 17-phenyl trinor Prostaglandin F2¦Á(17-phenyl trinor PGF2¦Á). A number of 17-phenyl trinor PGF2¦Á derivatives have been approved for the treatment of glaucoma.1,2,3,4…

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Trifluridine is an anti-herpesvirus antiviral agent by interacting viral DNA replication, used primarily on the eye.

prudect name : Trifluridine is an anti-herpesvirus antiviral agent by interacting viral DNA replication, used primarily on the eye.Trifluridine Synonyms: CAS NO: 70-00-8Molecular Formula: C10H11F3N2O5Molecular Weight: 296.20Purity: 98% minSolubility: In…

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