prudect name : Latanoprost acidSynonyms: LT-AcidCAS NO: 41639-83-2Molecular Formula: C23H34O5Molecular Weight: 390.51Purity: 98% minSolubility: Storage:

 June 21, 2017

prudect name : Latanoprost acid Synonyms: LT-AcidCAS NO: 41639-83-2Molecular Formula: C23H34O5Molecular Weight: 390.51Purity: 98% minSolubility: Storage: -20°C GSK-1349572 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18523009

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Linifanib (ABT-869) is a structurally novel, potent RTK and VEGF and PDGF receptor families inhibitor with IC50 of 0.2, 2, 4, and 7 nM for human endothelial cells, PDGFR-¦Â, KDR, and CSF-1R, respectively. It has much less activity (IC50s > 1 ¦ÌM) against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. In vivo ABT-869 is effective orally in the mechanism-based murine models of VEGF-induced uterine edema (ED50 = 0.5 mg/kg) and corneal angiogenesis ( >50%inhibition, 15 mg/kg ).

prudect name : Linifanib (ABT-869) is a structurally novel, potent RTK and VEGF and PDGF receptor families inhibitor with IC50 of 0.2, 2, 4, and 7 nM for human endothelial…

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prudect name : LynestrenolSynonyms: CAS NO: 52-76-6Molecular Formula: C20H28OMolecular Weight: 284.44Purity: 98% minSolubility: Storage: −20°C

prudect name : Lynestrenol Synonyms: CAS NO: 52-76-6Molecular Formula: C20H28OMolecular Weight: 284.44Purity: 98% minSolubility: Storage: −20°C GM-6001 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18522996

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LY2603618 (IC-83) is a highly selective Chk 1 inhibitor with potential antitumor activity. LY2603618 (IC-83) binds to and inhibits the activity of chk1, which may prevent the repair of DNA caused by DNA-damaging agents, thus potentiating the antitumor efficacies of various chemotherapeutic agents. Chk1, an ATP-dependent serine-threonine kinase, is a key component in the DNA replication-monitoring checkpoint system and is activated by double-stranded breaks (DSBs); activated chk1 is overexpressed by a variety of cancer cell types.

prudect name : LY2603618 (IC-83) is a highly selective Chk 1 inhibitor with potential antitumor activity. LY2603618 (IC-83) binds to and inhibits the activity of chk1, which may prevent the…

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prudect name : Latanoprost Lactone DiolSynonyms: LT-DICAS NO: 145667-75-0Molecular Formula: C18H24O4Molecular Weight: 304.38Purity: 98% minSolubility:

prudect name : Latanoprost Lactone Diol Synonyms: LT-DICAS NO: 145667-75-0Molecular Formula: C18H24O4Molecular Weight: 304.38Purity: 98% minSolubility: Storage: -20¡æ GSK2118436A References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18522975

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LY2886721 is an BACE inhibitor used for the treatment of Alzheimer¡¯s Disease.

prudect name : LY2886721 is an BACE inhibitor used for the treatment of Alzheimer¡¯s Disease.LY 2886721 hydrochloride salt Synonyms: CAS NO: 1262036-49-6Molecular Formula: C18H16F2N4O2S.HClMolecular Weight: 426.87Purity: 98% minSolubility: In DMSOStorage:…

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LY335979(Zosuquidar) is a selective Pgp (P-glycoprotein) inhibitor with a Ki of 59 nM, and does not modulate MRP-mediated resistance by MRP1 (ABCC1) and MRP2 (ABCC2). LY335979 significantly enhanced the survival of mice implanted with Pgp-expressing murine leukemia (P388/ADR) when administered in combination with either daunorubicin, doxorubicin or etoposide. Coadministration of LY335979 with paclitaxel compared to paclitaxel alone significantly reduced the tumor mass of the Pgp-expressing UCLA-P3.003VLB lung carcinoma in a xenograph model. LY335979 was without significant effect on the pharmacokinetics of these anticancer agents.

prudect name : LY335979(Zosuquidar) is a selective Pgp (P-glycoprotein) inhibitor with a Ki of 59 nM, and does not modulate MRP-mediated resistance by MRP1 (ABCC1) and MRP2 (ABCC2). LY335979 significantly…

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prudect name : LevonorgestrelSynonyms: CAS NO: 797-63-7Molecular Formula: C21H28O2Molecular Weight: 312.45Purity: 98% minSolubility: Storage: −20°C

prudect name : Levonorgestrel Synonyms: CAS NO: 797-63-7Molecular Formula: C21H28O2Molecular Weight: 312.45Purity: 98% minSolubility: Storage: −20°C FK 866 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18522906

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LY2886721 is an oral, small molecule of ¦Â-site amyloid protein cleaving enzyme (BACE) inhibitor with the potential to inhibit the synthesis of ¦Â-amyloid and thereby to slow the clinical progression of AD.LY2886721 can also target¦Ã-secretase to nhibit the synthesis of ¦Â-amyloid.

prudect name : LY2886721 is an oral, small molecule of ¦Â-site amyloid protein cleaving enzyme (BACE) inhibitor with the potential to inhibit the synthesis of ¦Â-amyloid and thereby to slow…

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LDN193189 is a highly potent small molecule BMP inhibitor with IC50 of 5 and 30 nM for ALK2 and ALK3, respectively. LDN193189 also inhibits BMP type I receptors ALK6 (TGF¦Â1/BMP signaling) and subsequent SMAD phosphorylation. LDN193189 inhibits FOP and ectopic ossification and a potential agent in the treatment of NSCLC lung tumors. LDN193189 affects not only the Smad but also the non-Smad signalling pathways induced by either BMP2, BMP6 or GDF5. The activation of p38, ERK1/2 and Akt in C2C12 cells was inhibited by LDN193189.

prudect name : LDN193189 is a highly potent small molecule BMP inhibitor with IC50 of 5 and 30 nM for ALK2 and ALK3, respectively. LDN193189 also inhibits BMP type I…

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