prudect name : LamivudineSynonyms: CAS NO: 134678-17-4Molecular Formula: C8H11N3O3SMolecular Weight: 229.25Purity: 99% minSolubility: Storage: −20°C

 June 21, 2017

prudect name : Lamivudine Synonyms: CAS NO: 134678-17-4Molecular Formula: C8H11N3O3SMolecular Weight: 229.25Purity: 99% minSolubility: Storage: −20°C WAY252623 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18523293

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prudect name : LopinavirSynonyms: CAS NO: 192725-17-0Molecular Formula: C37H48N4O5Molecular Weight: 628.80Purity: 99% minSolubility: Storage: −20°C

prudect name : Lopinavir Synonyms: CAS NO: 192725-17-0Molecular Formula: C37H48N4O5Molecular Weight: 628.80Purity: 99% minSolubility: Storage: −20°C GS 1101 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18523271

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LY2801653 is an orally available, small molecule inhibitor of the proto-oncogene c-Met (mesenchymal-epithelial transition, also known as hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c-Met inhibitor LY2801653 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein. This agent has potent anti-tumor efficacy in mono- and combination therapy in a broad range of cancers. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays key roles in tumor cell proliferation, survival, invasion, metastasis, and tumor angiogenesis.

prudect name : LY2801653 is an orally available, small molecule inhibitor of the proto-oncogene c-Met (mesenchymal-epithelial transition, also known as hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c-Met…

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LY2811376 is an additional ¦Ã-secretase inhibitor. It in preclinical work in dogs reduced A¦Â in CSF.

prudect name : LY2811376 is an additional ¦Ã-secretase inhibitor. It in preclinical work in dogs reduced A¦Â in CSF.LY2811376 Synonyms: CAS NO: 1194044-20-6Molecular Formula: C15H14F2N4SMolecular Weight: 320.36Purity: 98% minSolubility: In…

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LY2228820 is a novel and potent p38MAPK inhibitor: in vitro kinase enzyme activity showed that the IC50 for p38¦ÁMAPK and p38¦ÂMAPK were 7 nM and 3 nM, respectively, while that for p38¦ÄMAPK, p38¦ÃMAPK and a panel of 172 additional kinases was more than 20 µM. Phosphorylation of MAPKAPK2 and/or HSP27, down stream targets of p38MAPK, was significantly inhibited by LY in both MM cell lines and LT-BMSCs.

prudect name : LY2228820 is a novel and potent p38MAPK inhibitor: in vitro kinase enzyme activity showed that the IC50 for p38¦ÁMAPK and p38¦ÂMAPK were 7 nM and 3 nM,…

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3-(1-Carboxy-2-(3,4-dihydroxyphenyl)ethyl) 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofurancarboxylate (2S-(2alpha,3beta(S*),4(E(S*))))-;3-Benzofurancarboxylic acid, 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethyl) ester, (2S-(2alpha,3beta(S*),4(E(S*))))-;Salvialic acid B;Danfensuan B

prudect name : 3-(1-Carboxy-2-(3,4-dihydroxyphenyl)ethyl) 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofurancarboxylate (2S-(2alpha,3beta(S*),4(E(S*))))-;3-Benzofurancarboxylic acid, 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethyl) ester, (2S-(2alpha,3beta(S*),4(E(S*))))-;Salvialic acid B;Danfensuan BLithospermic acid B Synonyms: CAS NO: 121521-90-2Molecular Formula: C36H30O16Molecular Weight: 718.61Purity: 98% minSolubility: In DMSOStorage: -20°C CP690550…

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LY2157299 is a novel selective small molecule transforming growth factor beta receptor (TGF-¦ÂR) kinase inhibitor with IC50 of 86 nM and 2 nM for T¦ÂR1 and 2 nM, respectively. LY2157299 was well tolerated at both doses of 40 and 80 mg and no drug-related CTCAE Grade 3 or 4 toxicities were observed. Absorption of LY2157299 was rapid as determined by plasma concentrations at the first sampling time (0.5 hours). Daily oral administration of LY2157299 was safe and well tolerated at the two dose levels and the pharmacokinetic profile was consistent with the prediction derived from preclinical PK/PD model. As would be predicted for an inhibitor of TGF-¦Â signaling, LY2157299 blocked the phsophorylation of Smad2 but had no effect on fibroblast growth factor (FGF) or platelet-derived growth factor (PDGF) signaling. However, another study reported that LY2157299 induced angiogenesis and enhanced VEGF- and basic-fibroblast-growth-factor- induced angiogenesis in a Matrigel-plug assay, whereas adding an alpha5-integrin -neutralizing antibody to the Matrigel selectively inhibited this enhanced response.

prudect name : LY2157299 is a novel selective small molecule transforming growth factor beta receptor (TGF-¦ÂR) kinase inhibitor with IC50 of 86 nM and 2 nM for T¦ÂR1 and 2…

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prudect name : Lecirelin (Dalmarelin) AcetateSynonyms: CAS NO: 61012-19-9Molecular Formula: C59H84N16O12Molecular Weight: 1209.4Purity: 98%

prudect name : Lecirelin (Dalmarelin) Acetate Synonyms: CAS NO: 61012-19-9Molecular Formula: C59H84N16O12Molecular Weight: 1209.4Purity: 98% minSolubility: in DMSOStorage: -20oC CH-5424802 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18523087

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prudect name : LaninamivirSynonyms: CAS NO: 203120-17-6Molecular Formula: C13H22N4O7Molecular Weight: 346.34Purity: 98% minSolubility: In DMSOStorage:

prudect name : Laninamivir Synonyms: CAS NO: 203120-17-6Molecular Formula: C13H22N4O7Molecular Weight: 346.34Purity: 98% minSolubility: In DMSOStorage: −20°C NVP-AUY 922 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18523061

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prudect name : Latanoprost LactolSynonyms: LT-TRICAS NO: 352276-28-9Molecular Formula: C18H26O4Molecular Weight: 306.40Purity: 98% minSolubility: Storage:

prudect name : Latanoprost Lactol Synonyms: LT-TRICAS NO: 352276-28-9Molecular Formula: C18H26O4Molecular Weight: 306.40Purity: 98% minSolubility: Storage: -20¡æ SPI1005 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18523031

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