LDN-212854 is a novel BMP inhibitor that exhibits substantially greater selectivity for BMP versus the TGF-¦Â type I receptors; possesses a bias towards ALK2(IC50=1.3 nM) versus ALK1 and ALK3 compared to other inhibitors.

June 21, 2017

prudect name : LDN-212854 is a novel BMP inhibitor that exhibits substantially greater selectivity for BMP versus the TGF-¦Â type I receptors; possesses a bias towards ALK2(IC50=1.3 nM) versus ALK1…

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4-[(2R)-2-[(1R)-2,2,2-Trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-2-(trifluoromethyl)benzonitrile

prudect name : 4-[(2R)-2-[(1R)-2,2,2-Trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-2-(trifluoromethyl)benzonitrileLGD 4033;LGD-4033 Synonyms: CAS NO: 1165910-22-4Molecular Formula: C14H12F6N2OMolecular Weight: 338.25Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years VS 4718 References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18523927

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Latanoprost is a topical eye medication used to reduce pressure inside the eye. It is used to treat eye conditions, including glaucoma and ocular hypertension, in which increased pressure can lead to a gradual loss of vision.

prudect name : Latanoprost is a topical eye medication used to reduce pressure inside the eye. It is used to treat eye conditions, including glaucoma and ocular hypertension, in which…

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L189 is a DNA ligase I, III and IV inhibitor (IC50 values are 5, 9 and 5 ¦ÌM respectively) that blocks DNA binding. L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ). L189 specifically sensitizes cancer cells to DNA damage and increases the cytotoxicity of DNA-damaging agents. L189 will not only provide insights into the cellular function of these enzymes but also serve as lead compounds for the development of anticancer agents.

prudect name : L189 is a DNA ligase I, III and IV inhibitor (IC50 values are 5, 9 and 5 ¦ÌM respectively) that blocks DNA binding. L189 inhibits base excision…

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LCZ696, consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally bioavailable, dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) for hypertension and heart failure.

prudect name : LCZ696, consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally bioavailable, dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) for hypertension and heart failure.LCZ696 Synonyms: CAS NO:…

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Lomustine for the treatment of malignant tumors.

prudect name : Lomustine for the treatment of malignant tumors.Lomustine Synonyms: CeeNU, CCNUCAS NO: 13010-47-4Molecular Formula: C9H16ClN3O2Molecular Weight: 233.69Purity: 99%Solubility: In DMSOStorage: −20°C 2 years AP-23573 References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18523795

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Ledipasvir(GS5885) is an inhibitor of the hepatitis C virus NS5A protein. Ledipasvir is an experimental drug for the treatment of hepatitis C.

prudect name : Ledipasvir(GS5885) is an inhibitor of the hepatitis C virus NS5A protein. Ledipasvir is an experimental drug for the treatment of hepatitis C.Ledipasvir GS 588 Synonyms: CAS NO:…

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The new non-steroidal anti-inflammatory drugs.

prudect name : The new non-steroidal anti-inflammatory drugs.Licofelone Synonyms: CAS NO: 156897-06-2Molecular Formula: C23H22ClNO2Molecular Weight: 379.88Purity: ≥99%Solubility: Storage: −20°C 2 years GSK 2118436 References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18523733

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Luliconazole(NND 502; Lulicon) is useful for Anti-infective agents

prudect name : Luliconazole(NND 502; Lulicon) is useful for Anti-infective agentsLuliconazole Synonyms: CAS NO: 187164-19-8Molecular Formula: C14H9Cl2N3S2Molecular Weight: 354.28Purity: 98% minSolubility: In DMSOStorage: -20°C VX497 References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18523692

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4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol

prudect name : 4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanolLY2874455 Synonyms: CAS NO: 1254473-64-7Molecular Formula: C21H19Cl2N5O2Molecular Weight: 444.31Purity: 98% minSolubility: In DMSOStorage: −20°C VS-4718 References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18523643

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