VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.

June 21, 2017

prudect name : VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays…

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prudect name : Vancomycin hydrochlorideSynonyms: CAS NO: 1404-93-9Molecular Formula: C66H75Cl2N9O24.HClMolecular Weight: 1485.72Purity: 98% minSolubility: Storage:

prudect name : Vancomycin hydrochloride Synonyms: CAS NO: 1404-93-9Molecular Formula: C66H75Cl2N9O24.HClMolecular Weight: 1485.72Purity: 98% minSolubility: Storage: -20°C web site: www.medchemexpress.com

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VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.

prudect name : VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.VTP27999 HCL Synonyms: CAS NO: 1264191-73-2Molecular Formula: C26H41ClN4O5.HClMolecular Weight: 561.54Purity: 98% minSolubility:…

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Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections.

prudect name : Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections.Valganciclovir hydrochloride Synonyms: CAS NO:…

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Biological Activity of ABT-888(Veliparib): ABT-888 is a potent inhibitor of both PARP-1 and PARP-2 by [3H]NAD+ with Kis of 5.2 and 2.9 nmol/L, respectively.The compound has good oral bioavailability and crosses the blood-brain barrier. ABT-888 strongly potentiated temozolomide in the B16F10 s.c. murine melanoma model. In the MX-1 breast xenograft model(BRCA1 deletion and BRCA2 mutation), ABT-888 potentiated cisplatin, carboplatin, and cyclophosphamide,causing regression of established tumors, whereas with comparable doses of cytotoxic agents alone, only modest tumor inhibition was exhibited

prudect name : Biological Activity of ABT-888(Veliparib): ABT-888 is a potent inhibitor of both PARP-1 and PARP-2 by [3H]NAD+ with Kis of 5.2 and 2.9 nmol/L, respectively.The compound has good…

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Voriconazole (VFEND) is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections. These are generally seen in patients who are immunocompromised, and include invasive candidiasis, invasive aspergillosis, and certain emerging fungal infections.

prudect name : Voriconazole (VFEND) is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections. These are generally seen in patients who are immunocompromised, and…

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Vidofludimus(4SC-101; SC12267) is a novel immunosuppressive drug that inhibits DHODH; inhibits IL-17 secretion in vitro independently of effects on lymphocyte proliferation.

prudect name : Vidofludimus(4SC-101; SC12267) is a novel immunosuppressive drug that inhibits DHODH; inhibits IL-17 secretion in vitro independently of effects on lymphocyte proliferation.Vidofludimus(4SC-101; SC12267) Synonyms: CAS NO: 717824-30-1Molecular Formula:…

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PLX4032 is a highly selective inhibitor of BRAF kinase activity, with an IC50 of 44 nmol/L against V600E-mutant BRAF. [1] BRAFV600E cancer-causing mutation occurs in most melanomas and about eight percent of all solid tumors. [2] BRAF mutant melanoma cell strains were highly sensitive to PLX4032 with IC50 in the nM range (60ยจC450 nM), whereas BRAF wild-type cells were resistant, with IC50 2.4 ยฆรŒM or above.

prudect name : PLX4032 is a highly selective inhibitor of BRAF kinase activity, with an IC50 of 44 nmol/L against V600E-mutant BRAF. [1] BRAFV600E cancer-causing mutation occurs in most melanomas…

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Vinorelbine(KW-2307 base) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.

prudect name : Vinorelbine(KW-2307 base) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.Vinorelbine tartrate Synonyms: CAS NO: 125317-39-7Molecular Formula: C45H54N4O8.2(C4H6O6);C53H66N4O20Molecular Weight: 1079.12Purity:…

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prudect name : VRT752271Synonyms: CAS NO: 869886-67-9Molecular Formula: C21H23CI3N4O2Molecular Weight: 469.79Purity: 98% minSolubility: In DMSOStorage:

prudect name : VRT752271 Synonyms: CAS NO: 869886-67-9Molecular Formula: C21H23CI3N4O2Molecular Weight: 469.79Purity: 98% minSolubility: In DMSOStorage: -20°C web site: www.medchemexpress.com

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