VD/VDR-vd-vdr.com

Clofarabine is a second generation purine nucleoside analog with antineoplastic activity. It is phosphorylated intracellularly, which inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase, resulting in inhibition of DNA repair and synthesis of DNA and RNA. This nucleoside analog also disrupts mitochondrial function and membrane integrity, resulting in the release of pre-apoptotic factors, including cytochrome C and apoptotic-inducing factor, which activate apoptosis.

June 21, 2017

prudect name : Clofarabine is a second generation purine nucleoside analog with antineoplastic activity. It is phosphorylated intracellularly, which inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM)…

📌

0💬 read more

Cariprazine(RGH188) is a novel antipsychotic drug candidate that exhibits high selectivity and affinity to dopamine D3(Ki=0.09 nM) and D2 (Ki=0.5 nM) receptors and moderate affinity to serotonin 5-HT(1A) receptors.

prudect name : Cariprazine(RGH188) is a novel antipsychotic drug candidate that exhibits high selectivity and affinity to dopamine D3(Ki=0.09 nM) and D2 (Ki=0.5 nM) receptors and moderate affinity to serotonin…

📌

0💬 read more

Synonyms:2-[[2-[(4-Methoxyphenyl)amino]-4-pyrimidinyl]amino]ethanol

prudect name : Synonyms:2-[[2-[(4-Methoxyphenyl)amino]-4-pyrimidinyl]amino]ethanolCardiogenol C Synonyms: CAS NO: 671225-39-1Molecular Formula: C13H16N4O2Molecular Weight: 260.29Purity: 98% minSolubility: In DMSOStorage: -20 oC mGluR5 inhibitor References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1850690

📌

0💬 read more

prudect name : CladribineSynonyms: CAS NO: 4291-63-8Molecular Formula: C10H12ClN5O3Molecular Weight: 285.69Purity: 98% minSolubility: In DMSOStorage:

prudect name : Cladribine Synonyms: CAS NO: 4291-63-8Molecular Formula: C10H12ClN5O3Molecular Weight: 285.69Purity: 98% minSolubility: In DMSOStorage: −20°C CPI203 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18506855

📌

0💬 read more

CGI1746 is a small-molecule Bruton_acute_s tyrosine kinase (Btk) inhibitor.

prudect name : CGI1746 is a small-molecule Bruton_acute_s tyrosine kinase (Btk) inhibitor.CGI-1746 Synonyms: CAS NO: 910232-84-7Molecular Formula: C34H37N5O4Molecular Weight: 579.69Purity: 98% minSolubility: In DMSOStorage: -20 oC AMG 706 References PubMed…

📌

0💬 read more

GMX1778(CHS-828) is a potent inhibitor of NAD_addition_ biosynthesis enzyme NAMPT with IC50 <25 nM.

prudect name : GMX1778(CHS-828) is a potent inhibitor of NAD_addition_ biosynthesis enzyme NAMPT with IC50

📌

0💬 read more

Cetilistat is an inhibitor of pancreatic and gastrointestinal lipases. It has great treatment of obesity in both diabetic and non-diabetic patients.

prudect name : Cetilistat is an inhibitor of pancreatic and gastrointestinal lipases. It has great treatment of obesity in both diabetic and non-diabetic patients.cetilistat Synonyms: CAS NO: 282526-98-1Molecular Formula: C25H39NO3Molecular…

📌

0💬 read more

prudect name : ChlormethineSynonyms: CAS NO: 51-75-2Molecular Formula: C5H11Cl2NMolecular Weight: 156.05Purity: 99%Solubility: Storage: −20°C

prudect name : Chlormethine Synonyms: CAS NO: 51-75-2Molecular Formula: C5H11Cl2NMolecular Weight: 156.05Purity: 99%Solubility: Storage: −20°C 2 years PD-1/PD-L1 inhibitor 2 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18506688

📌

0💬 read more

Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae).

prudect name : Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae).Curcumin Synonyms: CAS NO: 458-37-7Molecular Formula: C21H20O6Molecular Weight:…

📌

0💬 read more

prudect name : CarmustinSynonyms: CAS NO: 154-93-8Molecular Formula: C5H9Cl2N3O2Molecular Weight: 214.05Purity: 99%Solubility: Storage: −20°C

prudect name : Carmustin Synonyms: CAS NO: 154-93-8Molecular Formula: C5H9Cl2N3O2Molecular Weight: 214.05Purity: 99%Solubility: Storage: −20°C 2 years Galunisertib References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18506595

📌

0💬 read more