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MDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo.

June 21, 2017

prudect name : MDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo.MDL 29951 Synonyms: CAS NO: 130798-51-5Molecular Formula: C12H9Cl2NO4Molecular Weight:…

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Macitentan is an orally active, non-peptide dual endothelin (ET)(A) and ET(B) receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).

prudect name : Macitentan is an orally active, non-peptide dual endothelin (ET)(A) and ET(B) receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).Macitentan…

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Monomethylauristatin F(MMAF) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than MMAE; antibody drug cytotoxin.

prudect name : Monomethylauristatin F(MMAF) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than MMAE; antibody drug cytotoxin.Monomethylauristatin F Synonyms: MMAFCAS…

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Moxifloxacin is a fourth-generation quinolone broad-spectrum antibiotics, the treatment of severe respiratory tract infections

prudect name : Moxifloxacin is a fourth-generation quinolone broad-spectrum antibiotics, the treatment of severe respiratory tract infectionsMoxifloxacin hydrochloride Synonyms: CAS NO: 186826-86-8Molecular Formula: C21H24FN3O4.HClMolecular Weight: 437.90Purity: 99%Solubility: Storage: −20°C 2…

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MGCD0103 (Mocetinostat) is a potent HDAC inhibitor with IC50 of 0.15, 0.29 and 1.66 ¦ÌM for HDAC 1, HDAC 2 and HDAC 3, respectively. In intact cells, MGCD0103 inhibited only a fraction of the total HDAC activity and showed long-lasting inhibitory activity even upon drug removal. MGCD0103 (Mocetinostat) induced hyperacetylation of histones, selectively induced apoptosis, and caused cell cycle blockade in various human cancer cell lines in a dose-dependent manner. MGCD0103 (Mocetinostat) exhibited potent and selective antiproliferative activities against a broad spectrum of human cancer cell lines (IC50 from 0.09-20 ¦ÌM)in vitro, and HDAC inhibitory activity was required for these effects. In vivo, MGCD0103 (Mocetinostat) significantly inhibited growth of human tumor xenografts in nude mice in a dose-dependent manner and the antitumor activity correlated with induction of histone acetylation in tumors.

prudect name : MGCD0103 (Mocetinostat) is a potent HDAC inhibitor with IC50 of 0.15, 0.29 and 1.66 ¦ÌM for HDAC 1, HDAC 2 and HDAC 3, respectively. In intact cells,…

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prudect name : MildronateSynonyms: CAS NO: 76144-81-5Molecular Formula: C6H14N2O2Molecular Weight: 146.19Purity: 99%Solubility: Storage: −20°C 2

prudect name : Mildronate Synonyms: CAS NO: 76144-81-5Molecular Formula: C6H14N2O2Molecular Weight: 146.19Purity: 99%Solubility: Storage: −20°C 2 years web site: www.medchemexpress.com References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18533395

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MilbemycinB; 5-O-demethyl-28-deoxy-25-(1E)-1,3-dimethyl-1-butenyl-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-; proheart;

prudect name : MilbemycinB; 5-O-demethyl-28-deoxy-25-(1E)-1,3-dimethyl-1-butenyl-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-; proheart;Moxidectin Synonyms: CAS NO: 113507-06-5Molecular Formula: C37H53NO8Molecular Weight: 639.82Purity: 98% minSolubility: In DMSOStorage: -20°C web site: www.medchemexpress.com References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18533369

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Mitoguazone is spermine adenosine uptake of S-methionine decarboxylase inhibitor,For acute myeloid or monocytic leukemia.

prudect name : Mitoguazone is spermine adenosine uptake of S-methionine decarboxylase inhibitor,For acute myeloid or monocytic leukemia.Mitoguazone Synonyms: CAS NO: 459-86-9Molecular Formula: C5H12N8Molecular Weight: 184.206Purity: 99%Solubility: In DMSOStorage: -20°C web…

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Methotrexate for the anti-folate class agents, mainly through the inhibition of dihydrofolate reductase obstacles to achieve the synthesis of tumor cells, and inhibit tumor cell growth and reproduction.

prudect name : Methotrexate for the anti-folate class agents, mainly through the inhibition of dihydrofolate reductase obstacles to achieve the synthesis of tumor cells, and inhibit tumor cell growth and…

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Miriplatin; SMP-11355; SM-11355; DACHPM; DACHPt(II)(Myr)2

prudect name : Miriplatin; SMP-11355; SM-11355; DACHPM; DACHPt(II)(Myr)2Miriplatin Synonyms: CAS NO: 141977-79-9Molecular Formula: C34H68N2O4PtMolecular Weight: 764.02Purity: 98% minSolubility: In DMSOStorage: -20°C web site: www.medchemexpress.com References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18533079

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