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Solifenacin succinate for bladder hyperactivity

June 21, 2017

prudect name : Solifenacin succinate for bladder hyperactivitySolifenacin succinate Synonyms: CAS NO: 242478-38-2Molecular Formula: C23H26N2O2.C4H6O4Molecular Weight: 480.55Purity: ≥99%Solubility: Storage: −20°C 2 years web site: www.medchemexpress.com

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alpha,alpha-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

prudect name : alpha,alpha-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrileSC 26196 Synonyms: CAS NO: 218136-59-5Molecular Formula: C27H29N5Molecular Weight: 423.55Purity: 98% minSolubility: In DMSOStorage: -20°C web site: www.medchemexpress.com

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SCH 900776 is not a potent inhibitor of Chk2 and CDK2 with IC50 of 1.5 ¦ÌM and 0.16 ¦ÌM, respectively. SCH 900776 shows no significant inhibition of cytochrome P450 human liver microsomal isoforms 1A2, 2C9, 2C19, 2D6, and 3A4. SCH 900776 induces a dose-dependent loss of DNA replication capability 24 hours after hydroxyurea exposure. SCH 900776 enhances the ¦Ã-H2AX response of hydroxyurea, 5-fluoruracil, and cytarabine. In combination with an antimetabolite, SCH 900776 induces accumulation of ¦Ã-H2AX within 2 hours, indicative of replication fork collapse and double stranded DNA breaks. Additionally, SCH 900776 suppresses accumulation of the Chk1 pS296 autophosphorylation in a dose-dependent manner. Exposure of proliferating WS1 cells to SCH 900776 is associated with rapid, dose-dependent accumulation of Chk1 pS345, indicating that cycling populations of normal cells induce Chk1 pS345 following exposure to SCH 900776 as part of a futile cycle, perhaps driven by AT-family kinases and DNA-PK.

prudect name : SCH 900776 is not a potent inhibitor of Chk2 and CDK2 with IC50 of 1.5 ¦ÌM and 0.16 ¦ÌM, respectively. SCH 900776 shows no significant inhibition of…

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SB 239063 is a potent and selective p38 MAPK inhibitor (IC50 = 44 nM for p38¦Á). SB 239063 displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580.

prudect name : SB 239063 is a potent and selective p38 MAPK inhibitor (IC50 = 44 nM for p38¦Á). SB 239063 displays > 220-fold selectivity over ERK, JNK1 and other…

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prudect name : SimvastatinSynonyms: CAS NO: 79902-63-9Molecular Formula: C25H38O5Molecular Weight: 418.57Purity: 98% minSolubility: In DMSOStorage:

prudect name : Simvastatin Synonyms: CAS NO: 79902-63-9Molecular Formula: C25H38O5Molecular Weight: 418.57Purity: 98% minSolubility: In DMSOStorage: -20°C web site: www.medchemexpress.com

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Selinexor (KPT-330) analog of KPT-185, is an orally bioavailable selective CRM1 inhibitor.

prudect name : Selinexor (KPT-330) analog of KPT-185, is an orally bioavailable selective CRM1 inhibitor.Selinexor (KPT-330) Synonyms: CAS NO: 1393477-72-9Molecular Formula: C17H11F6N7OMolecular Weight: 443.31Purity: 98% minSolubility: In DMSOStorage: −20°C 2…

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Solithromycin (CEM 101; OP 1068)is a novel fluoroketolide with improved antimicrobial effectiveness.

prudect name : Solithromycin (CEM 101; OP 1068)is a novel fluoroketolide with improved antimicrobial effectiveness.Solithromycin Synonyms: CEM 101; OP 1068CAS NO: 760981-83-7Molecular Formula: C43H65FN6O10Molecular Weight: 845.01Purity: 98% minSolubility: In DMSOStorage:…

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prudect name : SofalconeSynonyms: CAS NO: 64506-49-6Molecular Formula: C29H34O6Molecular Weight: 478.56Purity: ≥99%Solubility: In DMSOStorage: −20°C

prudect name : Sofalcone Synonyms: CAS NO: 64506-49-6Molecular Formula: C29H34O6Molecular Weight: 478.56Purity: ≥99%Solubility: In DMSOStorage: −20°C web site: www.medchemexpress.com

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STF-31 is an inhibitor of glucose transporter 1 (GLUT1, IC50 = 1 ¦ÌM).

prudect name : STF-31 is an inhibitor of glucose transporter 1 (GLUT1, IC50 = 1 ¦ÌM).STF-31 Synonyms: CAS NO: 724741-75-7Molecular Formula: C23H25N3O3SMolecular Weight: 423.53Purity: 98% minSolubility: DMSOStorage: -20¡æ web site:…

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SEA0400 is a novel and selective inhibitor of the Na+-Ca2+ exchanger with IC50 of 5-33 nM (inhibiting Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia).

prudect name : SEA0400 is a novel and selective inhibitor of the Na+-Ca2+ exchanger with IC50 of 5-33 nM (inhibiting Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia).SEA 0400…

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