(+)-Cloprostenol is a synthetic analog of prostaglandin F2¦Á (PGF2¦Á). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent than PGF2¦Á in terminating pregnancy when given subcutaneously at a daily dose of 0.125 ¦Ìg/kg in rats and hamsters, without the side effects associated with PGF2¦Á.1+)-Cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 value of 3 x 10-12 M.2 Cloprostenol isopropyl ester is a more lipid soluble form of cloprostenol.

June 21, 2017

prudect name : (+)-Cloprostenol is a synthetic analog of prostaglandin F2¦Á (PGF2¦Á). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent than PGF2¦Á in terminating pregnancy when given subcutaneously at a daily dose of 0.125 ¦Ìg/kg in rats and hamsters, without the side effects associated with PGF2¦Á.1+)-Cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 value of 3 x 10-12 M.2 Cloprostenol isopropyl ester is a more lipid soluble form of cloprostenol.
(+)-Cloprostenol isopropyl ester

Synonyms: CAS NO: 157283-66-4Molecular Formula: C₂₅H₃₅ClO₆Molecular Weight: 467.0Purity: 98% minSolubility: In DMSOStorage: -20°C

AMG 232 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18487222