SU11274 is a highly specific inhibitor of c-Met , with in vitro IC50 for the Met enzyme at 0.012 ¦Ìmol/L. The inhibitor did not affect other tyrosine kinase oncoproteins, including BCR-ABL, TEL-JAK2, TEL-PDGF_R, or TEL-ABL. Inhibition of the Met kinase activity by SU11274 led to time- and dose-dependent reduced cell growth.

June 21, 2017

prudect name : SU11274 is a highly specific inhibitor of c-Met , with in vitro IC50 for the Met enzyme at 0.012 ¦Ìmol/L. The inhibitor did not affect other tyrosine kinase oncoproteins, including BCR-ABL, TEL-JAK2, TEL-PDGF_R, or TEL-ABL. Inhibition of the Met kinase activity by SU11274 led to time- and dose-dependent reduced cell growth.
SU11274

Synonyms: PKI-SU11274CAS NO: 658084-23-2Molecular Formula: C₂₈H₃₀CIN₅O₄SMolecular Weight: 568.09Purity: 98% minSolubility: In DMSOStorage: −20°C

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