KN-62 is a selective, cell permeable inhibitor of calcium/calmodulin-dependent kinase II (CaMKII; IC50 = 900 nM).It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).

June 21, 2017

prudect name : KN-62 is a selective, cell permeable inhibitor of calcium/calmodulin-dependent kinase II (CaMKII; IC50 = 900 nM).It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).
KN-62

Synonyms: CAS NO: 127191-97-3Molecular Formula: C₃₈H₃₅N₅O₆S₂Molecular Weight: 721.84Purity: 98% minSolubility: In DMSOStorage: −20°C

PF06463922 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18521511