JZL184 is a useful tool for studying the effects of endogenous 2-AG signaling. JZL184 displays time-dependent inhibition of MAGL and exhibits >300-fold selectivity for MAGL over FAAH in vitro. JZL184 does not interact with CB1 or CB2 receptors and does not inhibit the 2-AG biosynthetic enzymes diacylglycerol lipase-¦Áand diacylglycerol lipase-¦Â, or the arachidonic acid¨Cmobilizing enzyme cytosolic phospholipase A2 group IVA.

June 21, 2017

prudect name : JZL184 is a useful tool for studying the effects of endogenous 2-AG signaling. JZL184 displays time-dependent inhibition of MAGL and exhibits >300-fold selectivity for MAGL over FAAH in vitro. JZL184 does not interact with CB1 or CB2 receptors and does not inhibit the 2-AG biosynthetic enzymes diacylglycerol lipase-¦Áand diacylglycerol lipase-¦Â, or the arachidonic acid¨Cmobilizing enzyme cytosolic phospholipase A2 group IVA.
JZL 184

Synonyms: CAS NO: 1101854-58-3Molecular Formula: C₂₇H₂₄N₂O₉Molecular Weight: 520.49Purity: 98% minSolubility: In DMSOStorage: -20°C

EPZ 5676 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18521027