Idasanutlin (RG-7388) is a potent and selective p53-MDM2 inhibitor with IC50 of 6 nM. Idasanutlin inhibits cell proliferation with IC50 of 30 nM, and induces dose-dependent p53 stabilization, cell cycle arrest, as well as cell apoptosis in cancer cells expressing wild-type p53.

June 21, 2017

prudect name : Idasanutlin (RG-7388) is a potent and selective p53-MDM2 inhibitor with IC50 of 6 nM. Idasanutlin inhibits cell proliferation with IC50 of 30 nM, and induces dose-dependent p53 stabilization, cell cycle arrest, as well as cell apoptosis in cancer cells expressing wild-type p53.
Idasanutlin (RG-7388);RG 7388

Synonyms: CAS NO: 1229705-06-9Molecular Formula: C₃₁H₂₉Cl₂F₂N₃O₄Molecular Weight: 616.48Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years

BIBF-1120 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18519261