G007-LK displays high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice.

June 21, 2017

prudect name : G007-LK displays high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice.
G007-LK

Synonyms: CAS NO: 1380672-07-0Molecular Formula: C₂₅H₁₆ClN₇O₃SMolecular Weight: 529.96Purity: 98% minSolubility: In DMSOStorage: -20 oC

BYL719 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18517223