GNF-5, an analogue of GNF-2 with improved pharmacokinetic properties, is a selective non-ATP competitive inhibitor of Bcr-Abl with an IC50 value of 0.22¡À0.1 uM (Wild type Abl).

June 21, 2017

prudect name : GNF-5, an analogue of GNF-2 with improved pharmacokinetic properties, is a selective non-ATP competitive inhibitor of Bcr-Abl with an IC50 value of 0.22¡À0.1 uM (Wild type Abl).
GNF-5;GNF 5

Synonyms: CAS NO: 778277-15-9Molecular Formula: C₂₀H₁₇F₃N₄O₃Molecular Weight: 418.37Purity: 98% minSolubility: in DMSOStorage: -20oC

DX-8951f References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18517217