GW3965 recruits the steroid receptor coactivator 1 to human LXR¦Á with EC50 of 125 nM in a cell-free ligand-sensing assay. GW3965 shows a potent antagonistic activity against hLXR¦Á and hLXR¦Â in cell-based assays with EC50 of 190 nM and 30 nM, respectively. Besides, GW3965 also sows excellent selectivity over other nuclear receptors.

June 21, 2017

prudect name : GW3965 recruits the steroid receptor coactivator 1 to human LXR¦Á with EC50 of 125 nM in a cell-free ligand-sensing assay. GW3965 shows a potent antagonistic activity against hLXR¦Á and hLXR¦Â in cell-based assays with EC50 of 190 nM and 30 nM, respectively. Besides, GW3965 also sows excellent selectivity over other nuclear receptors.
GW3965 HCl

Synonyms: CAS NO: 405911-17-3Molecular Formula: C₃₃H₃₁ClF₃NO₃.HClMolecular Weight: 618.52Purity: 98% minSolubility: In DMSOStorage: −20°C

MK7655 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18516689