GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases.

June 21, 2017

prudect name : GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases.
GSKJ1;GSK J1

Synonyms: CAS NO: 1373422-53-7Molecular Formula: C₂₂H₂₃N₅O₂Molecular Weight: 389.45Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years

PD-173074 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18516071