GDC-0973(XL-518; GDC 0973) is a selective inhibitor of MEK. GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors. Inappropriate activation of the MEK/ERK pathway promotes cell growth in the absence of exogenous growth factors.

June 21, 2017

prudect name : GDC-0973(XL-518; GDC 0973) is a selective inhibitor of MEK. GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors. Inappropriate activation of the MEK/ERK pathway promotes cell growth in the absence of exogenous growth factors.
GDC-0973

Synonyms: CAS NO: 934660-93-2Molecular Formula: C₂₁H₂₁F₃IN₃O₂Molecular Weight: 531.31Purity: 98% minSolubility: In DMSOStorage: -20°C

Isochlorogenic acid A References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18515840