EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity with Ki value of 2.5¡À0.5 nM. IC50 Value: 2.5¡À0.5 nM (PRC2-containing wild-type EZH2)

June 21, 2017

prudect name : EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity with Ki value of 2.5¡À0.5 nM.
IC50 Value: 2.5¡À0.5 nM (PRC2-containing wild-type EZH2)
EPZ6438; EPZ 6438; E-7438

Synonyms: CAS NO: 1403254-99-8Molecular Formula: C₃₄H₄₄N₄O₄Molecular Weight: 572.74Purity: 98% minSolubility: in DMSOStorage: -20oC

PZ-51 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513772