Danusertib (PHA-739358) is an Aurora kinase inhibitor for Aurora A/B/C with IC50 of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc.

June 21, 2017

prudect name : Danusertib (PHA-739358) is an Aurora kinase inhibitor for Aurora A/B/C with IC50 of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc.
Danusertib;PHA-739358

Synonyms: CAS NO: 827318-97-8Molecular Formula: C₂₆H₃₀N₆O₃Molecular Weight: 474.55Purity: 98% minSolubility: DMSOStorage: -20¡æ

BYL 719 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511224