Cyclopamine inhibits the hedgehog signaling pathway (Hh) by influencing the balance between the active and inactive forms of the Smoothened protein. The hedgehog signaling pathway carries out important functions in embryonic development and when it goes awry, deformities can occur. However, errant activation of the pathway can also trigger cancer in adult humans.

June 21, 2017

prudect name : Cyclopamine inhibits the hedgehog signaling pathway (Hh) by influencing the balance between the active and inactive forms of the Smoothened protein. The hedgehog signaling pathway carries out important functions in embryonic development and when it goes awry, deformities can occur. However, errant activation of the pathway can also trigger cancer in adult humans.
Cyclopamine

Synonyms: CAS NO: 4449-51-8Molecular Formula: C₂₇H₄₁NO₂Molecular Weight: 411.62Purity: 98% minSolubility: In DMSOStorage: −20°C

RC-1291 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18508495