Rabbit anti-M-CSF Polyclonal Antibody(Center)

April 20, 2025

Product Name :
Rabbit anti-M-CSF Polyclonal Antibody(Center)

Synonym :
Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; Lanimostim; Processed macrophage colony-stimulating factor 1; CSF1

Host :
Rabbit

Species Reactivity:
Human

Specificity :
This M-CSF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-257 amino acids from the Central region of human M-CSF.

Predicted Reactivity:
Mouse, Rat

Applications :
WB~~1:1000FC~~1:10~50IF~~1:10~50IHC-P~~1:10~50

Immunogen:

Concentration :

Purification :

Clonality:
Polyclonal Antibody

Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles

Research areas :
Cardiovascular;Immunology;Signal Transduction

Background :
Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.

UniProt :
P09603

Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Purified Rabbit Polyclonal Antibody (Pab) |Synonym Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; Lanimostim; Processed macrophage colony-stimulating factor 1; CSF1 |Host Rabbit |Specificity This M-CSF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-257 amino acids from the Central region of human M-CSF. |Species Reactivity Human |Predicted Reactivity Mouse, Rat |Applications WB~~1:1000FC~~1:10~50IF~~1:10~50IHC-P~~1:10~50 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |Research areas Cardiovascular;Immunology;Signal Transduction |Target |Background Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. |Cellular localization Cell membrane; Single-pass type I membrane protein |UniProt P09603 |References |References Lee,M.S., et.al.,J. Immunol. 183 (5), 3390-3399 (2009) |Tips:This product is for research use only. Not for use in diagnostic prodcedures.

Rabbit anti-M-CSF Polyclonal Antibody(Center)

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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