Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases.

June 21, 2017

prudect name : Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases.
Alvelestat (AZD9668)

Synonyms: CAS NO: 848141-11-7Molecular Formula: C₂₅H₂₂F₃N₅O₄SMolecular Weight: 545.53Purity: 98% minSolubility: in DMSOStorage: −20°C

898562-94-2 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18501954