AZD8330 potently and strongly inhibits MEK 1/2. AZD8330 has no inhibitory activity against over 200 other kinases including at concentrations up to 10 ¦ÌM. AZD8330 demonstrates sub-nanomolar potency in mechanistic (pERK) and low to sub-nanomolar potency in functional (proliferation) assays in MEK 1/2 inhibitor sensitive cell lines.

June 21, 2017

prudect name : AZD8330 potently and strongly inhibits MEK 1/2. AZD8330 has no inhibitory activity against over 200 other kinases including at concentrations up to 10 ¦ÌM. AZD8330 demonstrates sub-nanomolar potency in mechanistic (pERK) and low to sub-nanomolar potency in functional (proliferation) assays in MEK 1/2 inhibitor sensitive cell lines.
AZD8330

Synonyms: CAS NO: 869357-68-6Molecular Formula: C₁₆H₁₇FIN₃O₄Molecular Weight: 461.23Purity: 98% minSolubility: In DMSOStorage: -20°C

461432-26-8 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18501263