AP26113 is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstrated ability overcome Crizotinib resistance mediated by a L1196M mutation. Phase 2.

June 21, 2017

prudect name : AP26113 is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstrated ability overcome Crizotinib resistance mediated by a L1196M mutation. Phase 2.
AP26113

Synonyms: CAS NO: 1197958-12-5Molecular Formula: C₂₆H₃₄ClN₆O₂PMolecular Weight: 529.01Purity: 98% minSolubility: In DMSOStorage: -20 oC

850140-72-6 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18500966