Tubastatin A is substantially selective for all 11 HDAC isoforms and maintains over 1000-fold selectivity against all isoforms excluding HDAC8, where it has approximately 57-fold selectivity. In homocysteic acid (HCA) induced neurodegeneration assays, Tubastatin A displays dose-dependent protection against HCA-induced neuronal cell death starting at 5 ¦ÌM with near complete protection at 10 ¦ÌM.

June 21, 2017

prudect name : Tubastatin A is substantially selective for all 11 HDAC isoforms and maintains over 1000-fold selectivity against all isoforms excluding HDAC8, where it has approximately 57-fold selectivity. In homocysteic acid (HCA) induced neurodegeneration assays, Tubastatin A displays dose-dependent protection against HCA-induced neuronal cell death starting at 5 ¦ÌM with near complete protection at 10 ¦ÌM.
Tubastatin A HCl

Synonyms: CAS NO: 1310693-92-5Molecular Formula: C₂₀H₂₁N₃O₂.HClMolecular Weight: 371.86Purity: 98% minSolubility: In DMSOStorage: −20°C

web site: www.medchemexpress.com