SRT1720 is a selective activator of human SIRT1 (EC1.5 = 0.16 ¦ÌM and maximum activation = 781%) versus the closest sirtuin homologues, SIRT2 and SIRT3£¬(SIRT2: EC1.5 = 37 ¦ÌM£»SIRT3: EC1.5 > 300 ¦ÌM). This agent binds to the SIRT1 enzyme-peptide substrate complex at an allosteric site amino-terminal to the catalytic domain and lower the Michaelis constant for acetylated substrates.

June 21, 2017

prudect name : SRT1720 is a selective activator of human SIRT1 (EC1.5 = 0.16 ¦ÌM and maximum activation = 781%) versus the closest sirtuin homologues, SIRT2 and SIRT3£¬(SIRT2: EC1.5 = 37 ¦ÌM£»SIRT3: EC1.5 > 300 ¦ÌM). This agent binds to the SIRT1 enzyme-peptide substrate complex at an allosteric site amino-terminal to the catalytic domain and lower the Michaelis constant for acetylated substrates.
SRT1720

Synonyms: CAS NO: 1001645-58-4Molecular Formula: C₂₅H₂₃N₇OS.HClMolecular Weight: 506.02Purity: 98% minSolubility: In DMSOStorage: -20°C

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