Pimecrolimus caused a strong and dose-dependent inhibition of anti-IgE¨Cinduced release of histamine from mast cells and basophils (maximally 73% and 82%, respectively, at 500 nmol/L pimecrolimus) and of mast cell tryptase (maximally 75%) and a less pronounced inhibition of LTC4 (maximally 32%) and of calcium ionophore plus phorbol myristate acetate¨Cinduced mast cell TNF-¦Á release (90% maximum at 100 nmol/L pimecrolimus).

June 21, 2017

prudect name : Pimecrolimus caused a strong and dose-dependent inhibition of anti-IgE¨Cinduced release of histamine from mast cells and basophils (maximally 73% and 82%, respectively, at 500 nmol/L pimecrolimus) and of mast cell tryptase (maximally 75%) and a less pronounced inhibition of LTC4 (maximally 32%) and of calcium ionophore plus phorbol myristate acetate¨Cinduced mast cell TNF-¦Á release (90% maximum at 100 nmol/L pimecrolimus).
Pimecrolimus

Synonyms: Elidel, SDZ-ASM-981CAS NO: 137071-32-0Molecular Formula: C₄₃H₆₈ClNO₁₁Molecular Weight: 810.45Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years

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