AXL1717 (Picropodophyllotoxin) is an orally active insulin-like growth factor-1 receptor (IGF-1R) inhibitor with IC50 of 1 nM; exhibits little effect towards IR, FGFR, PDGFR and EGFR, and exerts no effects on microtubules and DNA topoisomerase II.

June 21, 2017

prudect name : AXL1717 (Picropodophyllotoxin) is an orally active insulin-like growth factor-1 receptor (IGF-1R) inhibitor with IC50 of 1 nM; exhibits little effect towards IR, FGFR, PDGFR and EGFR, and exerts no effects on microtubules and DNA topoisomerase II.
Picropodophyllotoxin

Synonyms: AXL-1717; AXL 1717CAS NO: 477-47-4 (17434-18-3)Molecular Formula: C₂₂H₂₂O₈Molecular Weight: 414.41Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years

web site: www.medchemexpress.com

References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18538736