PR-619 is a broad-range DUB inhibitor with potential for further development as a chemotherapeutic agent in cancer therapy.in vitro: PR-619 induces HCT116 cell death with EC50 values of 6.3 ¦ÌM . The general deubiquitylase (DUB) inhibitor, PR-619 attenuated KCa3.1 degradation, indicative of deubiquitylation being required for lysosomal delivery

June 21, 2017

prudect name : PR-619 is a broad-range DUB inhibitor with potential for further development as a chemotherapeutic agent in cancer therapy.in vitro: PR-619 induces HCT116 cell death with EC50 values of 6.3 ¦ÌM . The general deubiquitylase (DUB) inhibitor, PR-619 attenuated KCa3.1 degradation, indicative of deubiquitylation being required for lysosomal delivery
PR-619

Synonyms: CAS NO: 2645-32-1Molecular Formula: C7H5N5S2Molecular Weight: 223.28Purity: 98% minSolubility: In DMSOStorage: -20°C


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