PIK-90 is a potent and cell permeable PI3K inhibitor, with IC50 values (nM) of 11, 350, 18, and 58 for p110 ¦Á, ¦Â, ¦Ã and ¦Ä isoforms, low mTOR activity. Besides Val882 H-binding, PIK-90 uses its pyridine ring to enter the hydrophobic affinity pocket of the ATP binding site, where it also interacts with Lys833.

June 21, 2017

prudect name : PIK-90 is a potent and cell permeable PI3K inhibitor, with IC50 values (nM) of 11, 350, 18, and 58 for p110 ¦Á, ¦Â, ¦Ã and ¦Ä isoforms, low mTOR activity. Besides Val882 H-binding, PIK-90 uses its pyridine ring to enter the hydrophobic affinity pocket of the ATP binding site, where it also interacts with Lys833.
PIK-90

Synonyms: CAS NO: 677338-12-4Molecular Formula: C₁₈H₁₇N₅O₃Molecular Weight: 351.37Purity: 98% minSolubility: In DMSOStorage: −20°C

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