PF-06463922 is a novel, orally available, CNS-penetrant, ATP-competitive inhibitor of ALK/ROS1 with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively.

June 21, 2017

prudect name : PF-06463922 is a novel, orally available, CNS-penetrant, ATP-competitive inhibitor of ALK/ROS1 with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively.
PF 06463922

Synonyms: CAS NO: 1454846-35-5Molecular Formula: C₂₁H₁₉FN₆O₂Molecular Weight: 406.41Purity: 98% minSolubility: In DMSOStorage: -20 oC

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