PFI-1 binds to with cyclic AMP response binding protein with KD of 49 ¦ÌM. PFI-1 has an EC50 of 1.89 ¦ÌM for the inhibition of IL6 production from human blood mononuclear cells stimulated by LPS. PFI-1 induces dose-dependent reduction of cell viability in T4302 CD133+ cells. PFI-1 inhibits the proliferating of three NET cell lines (Bon-1 derived from a pancreatic NET, and H727 and H720 derived from lung NETs).

June 21, 2017

prudect name : PFI-1 binds to with cyclic AMP response binding protein with KD of 49 ¦ÌM. PFI-1 has an EC50 of 1.89 ¦ÌM for the inhibition of IL6 production from human blood mononuclear cells stimulated by LPS. PFI-1 induces dose-dependent reduction of cell viability in T4302 CD133+ cells. PFI-1 inhibits the proliferating of three NET cell lines (Bon-1 derived from a pancreatic NET, and H727 and H720 derived from lung NETs).
PFI-1(PF-6405761)

Synonyms: CAS NO: 1403764-72-6Molecular Formula: C₁₆H₁₇N₃O₄SMolecular Weight: 347.39Purity: 98% minSolubility: In DMSOStorage: -20°C

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