In vitro, PA-824 exhibits the high activity against multidrug-resistant clinical isolates from Asia (India and South Korea) and from throughout the United States (MIC < 1 ¦Ìg/ml) and is equally active against the drug-sensitive and multidrug-resistant isolates of M. tuberculosis (MICs range, 0.039 to 0.531 ¦Ìg/ml).A recent study shows that single-nucleotide polymorphisms of PA-824 resistance genes (fgd1 [Rv0407] and ddn [Rv3547]) don¡¯t significantly affect the PA-824 MICs (¡Ü 0.25 ¦Ìg/ml).

June 21, 2017

prudect name : In vitro, PA-824 exhibits the high activity against multidrug-resistant clinical isolates from Asia (India and South Korea) and from throughout the United States (MIC < 1 ¦Ìg/ml) and is equally active against the drug-sensitive and multidrug-resistant isolates of M. tuberculosis (MICs range, 0.039 to 0.531 ¦Ìg/ml).A recent study shows that single-nucleotide polymorphisms of PA-824 resistance genes (fgd1 [Rv0407] and ddn [Rv3547]) don¡¯t significantly affect the PA-824 MICs (¡Ü 0.25 ¦Ìg/ml).
PA-824

Synonyms: CAS NO: 187235-37-6Molecular Formula: C₁₄H₁₂F₃N₃O₅Molecular Weight: 359.26Purity: 98% minSolubility: In DMSOStorage: −20°C

web site: www.medchemexpress.com