Nutlin-3 is MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50 = 0.09 ¦ÌM) and activates p53. Antiproliferative agent;chemotherapeutic agent; induces apoptosis in cancer cells.

June 21, 2017

prudect name : Nutlin-3 is MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50 = 0.09 ¦ÌM) and activates p53. Antiproliferative agent;chemotherapeutic agent; induces apoptosis in cancer cells.
Nutlin-3a

Synonyms: CAS NO: 675576-98-4Molecular Formula: C₃₀H₃₀Cl₂N₄O₄Molecular Weight: 581.49Purity: 98% minSolubility: In DMSOStorage: −20°C

web site: www.medchemexpress.com

References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18537699