Membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 ¦Ìmol/L). Directly interacts with the hemopexin domain (PEX) of MT1-MMP, affecting homodimerization and repressing its pro-tumorigenic activity in vivo. Displays no effect on the catalytic activity of MT1-MMP or MMP-2.

June 21, 2017

prudect name : Membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 ¦Ìmol/L). Directly interacts with the hemopexin domain (PEX) of MT1-MMP, affecting homodimerization and repressing its pro-tumorigenic activity in vivo. Displays no effect on the catalytic activity of MT1-MMP or MMP-2.
NSC 405020

Synonyms: CAS NO: 7497-07-6Molecular Formula: C₁₂H₁₅Cl₂NOMolecular Weight: 260.16Purity: 98% minSolubility: In DMSOStorage: -20°C

web site: www.medchemexpress.com

References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18536271