Lenalidomide (Revlimid) is a derivative of thalidomide with antiangiogenic and antineoplastic properties(cell IC50= 10 ¦ÌM). [1] It was initially intended as a treatment for multiple myeloma.Lenalidomide inhibits TNF-alpha production, stimulates T cells, reduces serum levels of the cytokines vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), and inhibits angiogenesis. This agent also promotes G1 cell cycle arrest and apoptosis of malignant cells.

June 21, 2017

prudect name : Lenalidomide (Revlimid) is a derivative of thalidomide with antiangiogenic and antineoplastic properties(cell IC50= 10 ¦ÌM). [1] It was initially intended as a treatment for multiple myeloma.Lenalidomide inhibits TNF-alpha production, stimulates T cells, reduces serum levels of the cytokines vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), and inhibits angiogenesis. This agent also promotes G1 cell cycle arrest and apoptosis of malignant cells.
Lenalidomide

Synonyms: CAS NO: 191732-72-6Molecular Formula: C₁₃H₁₃N₃O₃Molecular Weight: 259.26Purity: 99%Solubility: In DMSOStorage: −20°C 2 years

web site: www.medchemexpress.com

References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18524799