LY315920(Varespladib) is a selective inhibitor of human, group IIA, nonpancreatic secretory PLA2 (sPLA2). In a chromogenic isolated enzyme assay, Varespladib inhibited sPLA2 activity with an IC50 of 9.6 ¡À1 nM or 7.3 ¡Á10-6 mole fraction, which approached the stiochiometric limit of this assay.

June 21, 2017

prudect name : LY315920(Varespladib) is a selective inhibitor of human, group IIA, nonpancreatic secretory PLA2 (sPLA2). In a chromogenic isolated enzyme assay, Varespladib inhibited sPLA2 activity with an IC50 of 9.6 ¡À1 nM or 7.3 ¡Á10-6 mole fraction, which approached the stiochiometric limit of this assay.
LY315920(Varespladib)

Synonyms: LY315920(Varespladib)CAS NO: 172732-68-2Molecular Formula: C₂₁H₂₀N₂O₅Molecular Weight: 380.39Purity: 98% minSolubility: In DMSOStorage: -20°C

web site: www.medchemexpress.com

References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18524951